R&D Ampoule Washing Machine

An R&D Ampoule Washing Machine is a specialized piece of pharmaceutical equipment designed for cleaning small glass ampoules (typically 1ml to 20ml) used in injectable drug production. These machines are particularly suited for research and development (R&D) labs, pilot-scale operations, and small-to-medium pharmaceutical facilities where high sterility, precision, and compliance with cGMP (Current Good Manufacturing Practices) standards are essential. Unlike larger rotary production models, R&D versions are often compact, semi-automatic, and versatile, allowing for low-volume batches while minimizing cross-contamination through independent washing circuits and filtered media.

Ampoule Washing Machine ensure thorough internal and external cleaning of ampoules using pressurized jets of purified water, Water for Injection (WFI), and compressed air, reducing particulate matter and microbial risks before filling and sealing.

R&D Ampoule Washing Machine Video

Key Features

• Compact and GMP-Compliant Design: Built with stainless steel 316 contact parts, polycarbonate or HDPE filters (5-10 micron), and acrylic covers for visibility and safety. Machines auto-stop if the cover is lifted and resume from the interruption point.

• Washing Mechanism: Multi-jet systems with solenoid valves and timers for sequential cycles (e.g., pre-wash, main wash, rinse, and air dry). Needles ensure positive pressure cleaning with minimal media usage.

• Capacity and Flexibility: Handles 1ml-20ml ampoules (some models up to 25ml); suitable for vials too. Batch loading via trays (e.g., 100-200 ampoules per cycle) with adjustable sequences.

• Controls: PLC/HMI touch screens for easy operation by semi-skilled staff; optional 21 CFR Part 11 compliance for data logging.

• Safety and Validation: Includes IQ/OQ/PQ documentation; low bottle breakage rate (<0.5%).

Operation Process

1. Loading: Ampoules are placed in trays or dumped from boxes into the machine’s loading area.

2. Washing Cycle: Trays lower onto centering pins; needles align with ampoule necks for jet washing (inside/outside) using filtered WFI/purified water and air.

3. Drying and Unloading: Air jets dry residues; cycle ends automatically. Trays are removed for inspection.

4. Maintenance: Simple disassembly for cleaning; filters replaceable.

Salient Features of Ampoule Washing Machine

• Compact GMP model.

• Solenoid valve system with timer operated mechanism controlled from HMI.

• PLC HMI based touch screen control panel.

• Suitable to wash 1ml to 20ml ampoules and 2ml to 100ml vials.

• Positive & pressurized jets through washing needle for pressure cleaning at minimum usages for washing media. Sound design concept of pressure tank for reverse & continuous supply of wash medias.

• Both internal & external washing ensuring absolutely & continuous ampoule after sequential washing.

• Acrylic top cover provided for clear view of washing during running of the machine.

• On-line poly carbonates housing with P.P. replaceable filter cartridge of 5 or 10 micron of water for best possible washing.

• All contact parts of washing media & Compressed Air are made from Stainless Steel316 or Polycarbonate HDPE or P.P. or any other FDA approved material.

• Machine automatically stop in case of acrylic top cover lifted during cycle operation and machine re-start from the point when cover is pushed down.

• Easy to operate machine can be operated by even semi-skilled operator.

• IQ/OQ documentation can be provided.

Technical Specification of Ampoule Washing Machine

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.