Pilot Scale Tablet Press Machine

Pilot Scale Tablet Press Machine

Pilot Scale Tablet Press Machine are specialized equipment used in the pharmaceutical, nutraceutical, and chemical industries for small to medium-batch production. They bridge the gap between laboratory-scale research and full commercial manufacturing, allowing for process validation, formulation testing, and scale-up trials while adhering to cGMP standards. Tablet Press Machine compress powder or granule formulations into tablets of various shapes, sizes, and layers. They are typically rotary or single-punch designs, offering outputs from a few thousand to over 100,000 tablets per hour, making them ideal for R&D, clinical trials, and pilot production runs.

Pilot Scale Tablet Press Machine Video

Key Features

  • Design and Operation: Fully or semi-automatic rotary presses with interchangeable turrets (e.g., 20D, 24B, or 30BB tooling). They support pre-compression for uniform density and can handle dry granulation or direct compression.

  • Control Systems: PLC with HMI touch screens (e.g., 6–15 inches) for real-time monitoring of parameters like compaction force, tablet weight, thickness, and hardness. Many include SCADA integration for data recording and alarm logs.

  • Versatility: Capable of producing mono-layer, bi-layer, or multi-layer tablets; some models accommodate dummy dies for trials with expensive materials.

  • Safety and Compliance: Hydraulic overload protection (HOS), nickel-plated components for durability, and cGMP-compliant designs for easy validation.

  • Output Capacity: Typically 1,000–144,000 tablets/hour, depending on turret stations and material properties.

Applications and Benefits

  • Applications: Ideal for developing new drug formulations, producing clinical trial batches, or optimizing processes before scaling to commercial lines. They handle a wide range of materials, from vitamins to specialty pharmaceuticals.

  • Benefits: Cost-effective for low-volume runs, reduces waste during trials, ensures consistent quality with automated controls, and supports regulatory compliance.

Salient Features of Pilot Scale Tablet Press Machine

  • cGMP Model.

  • Machine having motorized operation.

  • Hand wheel operation option offered for machine setting.

  • Stainless Steel covering on moving parts as per GMP requirements.

  • Suitable for round, oval and caplet shape tablets.

  • Small in size and easy to operate.

  • Less maintenance requires.

  • Parts can be easily remove for cleaning and autoclaving.

  • Compact design with outside hopper.

Pre Compression & Cleaning

Pre-compression is available to expel air trapped within the material in the die and to pre-densify the material prior to passing through the main compression rolls. This feature improves the quality of the product.

Spacious compression zone with acrylic guards gives a convenient access for cleaning purpose. Lower punch scraper seals prevent material passing through the lower punch guides into cam tracks. Ejection of excess powder reduced by proper selection of adjustment cam. Suction needle provided for clear dust particles during compression Process.

Technical Specification of  Small Tablet Press Machine

Models

TPM – 8D TPM – 8DB
No. of Stations Eight

Eight

Type of tooling

‘D’ ‘4-D’ & ‘4-B’
Production Output Up to 21000 / hour

6500 – 12000 per hour

Max. Operating Load

8 Tons 6 Tons
Max. Tablets Dia. (mm) 23mm

12.7mm

Max. Depth of Fill

20mm 17mm
Main Electric Motor 2 H.P. 1440 RPM

2 H.P. 1440 RPM

Power Voltage

415 V, 3 Phase, 50 Hz 415 V, 3 Phase, 50 Hz
v Length 750mm

750mm

v Width

650mm 650mm
v Height 1200mm

1200mm

Net Weight

360 Kgs. approx. 360 Kgs. approx.
Gross Weight 500 Kgs. approx.

500 Kgs. approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.


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