

Single Wheel Powder Filling Machine is a specialized piece of equipment primarily used in the pharmaceutical industry for accurately filling sterile dry powders into glass vials. It operates on a rotary wheel principle, where a single rotating wheel with multiple ports (typically 12) draws precise volumes of powder via vacuum suction and dispenses them into vials. This machine often integrates rubber stoppering (bunging) in a monoblock setup, ensuring cGMP compliance for sterile production. It’s designed for high accuracy and is commonly used for fill weights ranging from 50mg to 1,500mg per vial.
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Model | AI-SPFM |
Filling Range | 50mg. To 1.5 gms. In Single Dose, 1.5 gms. To 6 gms. In Double, Triple and Four Dose system |
Accuracy | ± 1% depending upon consistency and uniformity of bulk density of Injectable Powder under controlled level of humidity (below 28% RH) |
Humidity | Below 28% Rh required on machine to be arrange by customer |
Electrical | 415VAC 3Phase and 220 VAC Single Phase Power Supply (50 Hz) with A.C. Drive |
Power | 0. 5 H.P., 230 Volts, 1 Phase |
Compressed Air | Max. 2 Kg/Cm2 Oil Free |
Vacuum | 25″ Hg. @ 300 LPM displacement |
Conveyor Height | 815-940 mm |
Overall Dimensions | 2800 mm (L) x 840 mm (W) x 1675 mm, Model AHPF-120 |
Production Output | 40 fills/ min. for Single Dose, 20 fills/ min. for Double Dose, 12 fills/ min. for Triple Dose, 10 fills/ min. for Four Dose |
Net Weight | 250 Kgs. |
Gross Weight | 310 Kgs. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The Single Wheel Powder Filling Machine is a high-precision, rotary volumetric filler designed for sterile dry powder filling into glass vials (typically 5ml to 30ml). It uses a single rotating powder wheel with multiple ports (usually 12). Powder is drawn into the ports by vacuum, and a piston system with compressed air/nitrogen discharges the exact dose into the vial. It is often integrated with automatic rubber stoppering in a monoblock design for cGMP-compliant injectable production.
The machine supports a filling range of 50mg to 1.5g in single dose, and up to 6g with double/triple/four-dose systems. Filling accuracy is ±1% (depending on powder bulk density and humidity control below 28% RH). Production output is approximately 40 vials per minute for single dose, reducing with multiple doses (e.g., 20 fills/min for double dose). Output may vary by model and vial size.
It is flexible for 5ml to 30ml glass vials with quick change-over using minimum tools and change parts. It is ideal for sterile injectable powders such as antibiotics and other free-flowing to slightly cohesive pharmaceutical powders. All product contact parts are made of SS 316L for hygiene and autoclaving.
Key features include:
These ensure reliability, minimal downtime, and full cGMP compliance.
Maintaining humidity below 28% RH is critical to ensure powder flow consistency, prevent clumping, and achieve the stated filling accuracy. The machine is designed for easy maintenance — contact parts are removable for mandatory autoclaving, and most adjustments (doctor blade, wiper blade, etc.) are tool-less. Regular cleaning of the powder wheel, hopper, and sensors is recommended for optimal performance.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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