Our machines typically support ampoule sizes from 1 ml to 30 ml (with some high-speed models limited to 1–20 ml). Filling volumes generally range from 0.5 ml to 25–30 ml in a single dose, depending on the model and configuration, making them suitable for a variety of injectable formulations.

Output varies by model and number of heads: Single-head models reach up to 25 ampoules per minute, two-head up to 50, four-head up to 100, and eight-head up to 200 ampoules per minute (approximately 12,000 ampoules per hour). Higher-capacity configurations can support even greater throughput for large-scale production.

Sterilized ampoules are loaded into an infeed hopper and transferred via starwheel or cassette to a moving rack (often in an inclined or slant-travel position). The process includes pre-gassing with nitrogen, precise filling, post-gassing, pre-heating of the neck, flame sealing (using LPG and oxygen), and automatic collection of sealed ampoules. Features like “No Ampoule – No Filling” and neck centering ensure accuracy and minimize waste.

Contact parts are made from high-quality Stainless Steel 316L, while non-contact parts use Stainless Steel 304. All models are designed as compact units complying with cGMP standards, with options for nitrogen flushing, easy cleaning, and minimum changeover parts to support hygienic pharmaceutical production.

They are primarily used in the pharmaceutical industry for sterile injectables, vaccines, antibiotics, and biological products. They also serve the biotech, cosmetic (e.g., injectable fillers), chemical, and veterinary medicine sectors where precise, sterile liquid or powder packaging in glass ampoules is required.

Yes. Most models include nitrogen gas flushing before, during, and/or after filling to displace oxygen, prevent oxidation, and maintain sterility. Sealing is performed by pre-heating the ampoule neck followed by melting and forming a uniform hermetic seal using LPG and oxygen flames, with flow meters for precise regulation and rotation for even sealing.

Machines are designed for minimum changeover parts and time (especially between 1 ml and 10 ml sizes), full accessibility for easy maintenance, little overall maintenance, and straightforward cleaning. Large openings and stainless-steel construction further simplify upkeep.

Yes. We offer customized, cGMP-compliant machinery solutions tailored to specific production requirements. Options range from compact lab-scale and low-speed models to high-speed multi-head systems, with integration possibilities for upstream/downstream equipment and sterile environments.

We export worldwide to numerous countries including the United States, Canada, United Kingdom, Germany, France, India, China, Australia, Brazil, South Africa, UAE, Saudi Arabia, and many others across Africa, Asia, Europe, and the Americas. To discuss your requirements or request a quote, contact our engineering team via the website or at the provided contact details.