Rapid Mixer Granulator

Description

Rapid Mixer Granulator also known as a High Shear Mixer Granulator, is a specialized piece of equipment widely used in the pharmaceutical, food, chemical, and cosmetic industries for the efficient mixing of dry powders and the formation of wet granules. It plays a crucial role in the wet granulation process, which improves powder flowability, ensures content uniformity, and prepares materials for compression into tablets or capsules. By applying high shear forces, the RMG achieves rapid, uniform blending and granulation in a single vessel, reducing processing time and minimizing contamination risks. RMGs incorporate safety features like locked hatches, key interlocks, and overload protection to prevent accidents. Validation involves Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ), testing at varying loads for parameters like mixing time and granule uniformity. Always ensure oil-free process air and maintain equipment per manufacturer guidelines to avoid contamination.

  • Manual Control – Process Timer for Main Motor & Chopper. AMP Meter for Main Motor of chopper. On/Off Push Button.

 

  • Auto Control – PLC based with touch Screen and password level to feed the parameter of process for Wet / Dry Granulation.

 

  • Pre stored process parameter will help to achieve consistent product quality.

 

  • MMI (Touch Screen) for visualization of machine of specific process condition and data.

 

  • PLC indicates: Visualization of Machine process condition & date. Alarm Signal & Fault Message.

If you need details on specific models and pricing, let me know!

Working Principle of Rapid Mixer Granulator

The Rapid Mixer Granulator operates on the principle of high-shear wet granulation, combining mixing and milling in one bowl through mechanical agitation. The process relies on rising, whirling, and tumbling motions induced by the impeller and chopper. Here’s a step-by-step overview:

 

  • Dry Mixing: Powders are loaded into the bowl. The impeller runs at low to medium speed for 3-5 minutes to achieve uniform blending without granulation.

 

  • Wet Mixing (Binder Addition): A liquid binder is sprayed or poured in while the impeller continues at a higher speed. This wets the powder, forming a soft mass.

 

  • Granulation: The chopper activates at high speed for 5-10 minutes, shearing the wet mass into uniform granules. The impeller aids in fluidizing the material to prevent clumping.

 

  • Discharge: Granules are expelled through the bottom port via pneumatic operation, ensuring complete emptying at a 45-degree angle for efficiency.

 

Rapid Mixer Granulator working principles are based on two decisive factors essential for the intimate mixing system.

 

  • Spinning close to bottom of mixing bowl.

 

  • The impeller sets the entire mixture in whirling rising.

 

Tumbling motion ensuring a quick & even distribution of all dry components. This leads to an even distribution of all dry components & an even wetting of every granule. The large lumps occurred during wet mixing are broken up, by the strategically acted chopping tool rotating at 1440/2880 RPM.

 

The mixture can be discharged with the impeller running through outlet located on the side of the mixing bowl flush to the bottom. Easy accessibility for cleaning is guaranteed by the low profile. The mixing tool is easily removed from the drive shaft providing an unobstructed mixing area which may be cleaned very easily.

Technical Specification of Rapid Mixer Granulator

Model

RMG 10

RMG 25

RMG 100

RMG 150

RMG 250

RMG 400

RMG 600

Gross Capacity in Ltrs.

10

25

100

150

250

400

600

Working Capacity in Ltrs.

8

20

80

120

200

320

480

Main Motor – H. P.

2/3 H.P.

3/5 H.P.

7.5/10 H.P.

10/12.5 H.P.

22/30 H.P.

30/40 H.P.

40/50 H.P.

Impeller Motor RPM

75/150

75/150

75/150

75/150

100/150

100/150

100/150

Chopper Motor – H. P.

1/1.5 H.P.

1/1.5 H.P.

2/3 H.P.

3/5 H.P.

3/5 H.P.

5/7.5 H.P.

5/7.5 H.P.

Chopper Motor RPM

1500/3000

1500/3000

1500/3000

1500/3000

1500/3000

1500/3000

1500/3000

Weight Kgs. Approx.

425

650

1400

1600

2000

2500

3000

Length in mm approx.

1450

1800

1900

2100

2150

2750

2850

Width in mm approx.

600

1200

1300

1900

1900

2420

2530

Height in mm approx.

950

1400

1450

1500

1650

1900

2070

Lid Opening Height in mm approx.

1060

1600

2150

2300

2550

2950

3250

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Mixer, Blender and Dryer

Applications of Mixer, Blender and Dryer

Advantages of Rapid Mixer Granulator

Efficiency: Combines mixing and granulation in one step, saving time and space compared to traditional methods.

Uniformity: High shear ensures consistent granule size and content distribution, critical for drug efficacy.

Versatility: Handles dry/wet mixing, aqueous/solvent granulation; scalable from lab (5 kg) to production capacities.

Safety and Cleanliness: GMP-compliant designs with easy cleaning, interlocks, and contamination controls.

Low Power Use: Energy-efficient compared to other blenders, with minimal heat generation.

Key Features of Rapid Mixer Granulator

The Rapid Mixer Granulator typically consists of the following main parts:

 

  • Mixing Bowl: A conical or cylindrical vessel where materials are loaded. It features a discharge port at the bottom, operated by a pneumatic cylinder for easy unloading.

 

  • Impeller (Main Agitator): A bottom-entry blade that rotates at variable speeds to mix and shear powders, creating a tumbling motion for uniform distribution.

 

  • Chopper: A high-speed side-mounted blade that breaks down agglomerates and forms granules by cutting and milling the wet mass.

 

  • Liquid Binder Inlet: Allows controlled addition of binders during wet mixing.

 

  • Control System: Includes variable speed controls, timers, and safety interlocks.

 

  • Pneumatic and Electrical Systems: Ensure safe operation, with features like oil-free, dust-free process air.

FAQ for Rapid Mixer Granulator

The RMG operates on high-shear wet granulation principle. Powders are loaded into the bowl and mixed uniformly by the bottom-driven impeller. Binder solution is then added while the impeller runs at higher speed. The high-speed chopper (side-mounted) breaks down lumps and forms uniform granules. The process includes dry mixing, wet mixing, and granulation stages, followed by pneumatic discharge.

We offer a complete range from lab to production scale:

  • RMG 10: 8 Ltrs working capacity
  • RMG 25: 20 Ltrs working capacity
  • RMG 100: 80 Ltrs working capacity
  • RMG 150: 120 Ltrs working capacity
  • RMG 250: 200 Ltrs working capacity
  • RMG 400: 320 Ltrs working capacity
  • RMG 600: 480 Ltrs working capacity

Larger custom capacities are also available.

It is widely used in:

  • Pharmaceutical Industry
  • Biotech Industry
  • Ayurvedic & Herbal Industry
  • Nutraceutical Industry
  • Cosmetic Industry
  • Food Processing and Chemical Industries

It excels in wet granulation processes requiring uniform granules with excellent flow properties.

Key Features:

  • SS 316/316L contact parts with mirror polish
  • Bowl design with no dead spaces
  • High-speed impeller and chopper with variable speed
  • Pneumatic discharge, safety interlocks, and limit switches
  • Manual or PLC with HMI control options
  • Meets cGMP & FDA norms

Benefits: Short processing time, uniform granules, hygienic operation, easy cleaning, better productivity, and scalability.

Countries We Export to

United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba

Partner with Industry Experts

Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.

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