In the pharmaceutical manufacturing industry, maintaining impeccable hygiene and sterility is non-negotiable, especially for injectable products packaged in glass ampoules. An Automatic Rotary Ampoule Washing Machine is a specialized, high-tech solution designed to clean ampoules both internally and externally with precision, ensuring complete removal of contaminants while meeting stringent cGMP (Current Good Manufacturing Practice) standards.
This advanced pharmaceutical ampoule washing machine minimizes direct contact between machine components and glass ampoules, significantly reducing the risk of particle generation or cross-contamination. It has become an essential piece of equipment for pharmaceutical companies, veterinary medicine manufacturers, and biotech facilities that demand the highest levels of cleanliness before sterile filling operations.
Before any glass ampoule enters the sterile filling chamber, it must undergo thorough internal and external cleaning to eliminate dust, fibers, microbes, and residues. Any compromise in this stage can affect product safety and regulatory compliance. Leading manufacturers like Adinath have engineered reliable rotary ampoule washing machines that deliver consistent, validated cleaning results while optimizing production efficiency.
Ampoules fed from the infeed tray are received by an infeed worm and transferred to the infeed star wheel. Grippers then pick up each ampoule from the infeed star wheel, invert it into the neck-down position over the washing needles, and travel together with the needle bar during the washing cycle. This neck-down orientation above the washing needles maximises contact time once the needles enter the ampoule neck.
The machine is equipped with six independent washing stations, each fitted with six needles, to ensure thorough cleaning. The washing sequence can be adjusted according to specific requirements. An external wash station is also provided for optimum external cleaning of the ampoules.
On completion of the cycle, the washed ampoules are inverted back to the neck-up position and transferred to the output star wheel. From there they can be collected on an output tray or pushed directly into a tunnel.
An optional separate pumping station supplies the correct volume of water at the required pressure. In the absence of a separate pumping station, a re-circulation and siliconization system can be supplied on request.
INTERNAL CLEANING The machine is fitted with six internal cleaning stations, each carrying six cleaning needles, giving a total of 36 needles. Every station is supplied through a dedicated pipe connected to the cleaning-media preparation area. This arrangement reduces the risk of particle generation, simplifies maintenance and cleaning, and saves time.
EXTERNAL CLEANING Three external cleaning stations are mounted in a fixed position above the ampoules and can be readily adjusted for height, angle and lateral position. Each station receives cleaning media through a pipe connected to the same media-preparation area.
CLEANING MEDIA PRINCIPLE The WFI, purified-water and air cleaning stations are synchronised with the ampoule by reciprocating motion. Media are delivered only during the forward stroke of the needles. WFI consumption is further reduced by collecting the water in a re-circulating tank for subsequent use in the pre-washing station.
Model | AVRW 120 | AVRW 240 |
Production Output | Up to 100 per minute | Up to 200 per minute |
Ampoule Diameter | 9mm to 21.5mm | 9mm to 21.5mm |
Ampoule Height | 60mm to 140mm | 60mm to 140mm |
Power Load | 4 H.P. | 5.5 H.P. |
Power Voltage | 440 Volts, 3 Phase 50 Hertz, 4 wire system | 440 Volts, 3 Phase 50 Hertz, 4 wire system. |
Optional Accessories |
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Utility |
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Water Tank & Pump | 3 nos. each with 25 liters Capacity & Centrifugal pump | 3 nos. each with 25 liters Capacity & Centrifugal pump |
Overall Dimension: | 2050mm (L) X 2000mm (W) X 1210mm (H) approx. | 2450mm (L) X 2000mm (W) X 1300mm (H) approx. |
Net Weight | 700 kgs. approx. | 900 kgs. approx. |
Gross Weight | 1000 kgs. approx. | 1300 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
1st wash | Recycled Water (WFI) |
2nd wash | Compressed Air |
3rd wash | DM Water |
4th wash | Compressed Air |
5th wash | Water for Injection (WFI) |
6th wash | Compressed Air |
The machine is available in two models:
It handles 1ml to 20ml glass ampoules with diameters from 9mm to 21.5mm and heights from 60mm to 140mm. The washing sequence and speed can be easily adjusted as per requirement.
Ampoules are fed automatically via an infeed starwheel. Special grippers pick them up, invert them (neck down), and move them over six washing stations equipped with needles. The standard cycle includes 3 water washes and 3 compressed air washes in independent circuits to prevent cross-contamination:
After washing, ampoules are re-inverted (neck up) and discharged. An external wash is also provided for complete cleaning.
All product contact parts are made of AISI 316L Stainless Steel, while non-contact parts use AISI 304 Stainless Steel and engineering plastics. The machine is a complete cGMP model with smooth finishes and treated welding joints. It can be supplied with IQ/OQ/DQ documentation and optional 21 CFR Part 11 compliant PLC & HMI system for validation and regulatory requirements.
The machine requires:
Optional accessories include:
Yes — Adinath International Automatic Rotary Ampoule Washing Machine complies to cGMP, MHRA, FDA and WHO-GMP standards, with optional CE marked equipments and 21 CFR Part 11 software compliance for the HMI/PLC. Machine contact parts having Stainless Steel 316L grade materials with validation documents having IQ, OQ, DQ validation protocols as optional. Organization is ISO 9001:2015 certified.
Manufacturing lead time is generally 7 to 14 weeks from order confirmation. Further it takes 2 to 8 weeks for international shipping depending upon destination. Order can be expediate sooner or later as per specific buying requirements. Destination specific certifications like US FDA, EU, ANVISA, SFDA. CE can add 3 to 6 weeks additionally.
Yes, Adinath International Automatic Rotary Ampoule Washing Machine export this machine to more than 48 countries of this world including America, Europe, Asia, Middle East, Africa, CIS and Australia sub continents. Please visit our clientele page for complete list of our customers worldwide. Located at Ahmedabad, India having world class infrastructure.
Service of skilled engineers and technicians provided for technical support of supplied equipments. Installations, commissioning, training and IQ, OQ, DQ validations performed by qualified engineers. Remote support through video call, phone, email and other modes provided for international installations. Spare parts of “Machine name” stocked at our premises in Ahmedabad and shipped immediately after ordering. Standard 12 months manufacturing warranty included with supplied equipment.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.
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