Bottle Dry Injectable Filling Machine often referred to as a Dry Powder Injectable Filling Machine is specialized pharmaceutical equipment designed for the precise filling of sterile dry powders into glass vials or bottles. These powders are typically used for injectable medications that are reconstituted with a solvent before administration. Common applications include antibiotics, vaccines, and other heat-sensitive drugs that can’t be stored as liquids. The machines ensure aseptic processing to maintain sterility, with filling accuracies often within ±2% for doses ranging from 50mg to 1,500mg. Injectable Filling Machine are critical in cGMP-compliant environments, often integrated into cleanrooms or under laminar flow hoods. They typically combine filling with secondary operations like rubber stoppering or capping to minimize contamination risks.
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The incoming sterilized dry bottle is fed through the in-feed turn table. Suitable guide supply bottles on to flat conveyor belt at the required speed for feeding. There is filling head mounted on machine top plate in the same line. When bottle reaches to the mechanical holder detained filling station, Bottle sensor sense the bottles and Magnetic clutch starts to rotate which is mounted on auger shaft. It fills the desired amount of powder into the bottle through auger, where rotation time is previously determined. Duly filled bottles go upward on to the sealing station with the help of SS conveyor belt.
Models | AI-DPM 12 | AI-DPM 16 |
Production Output | Up to 80 bottles/minute | Up to 120 bottles/minute |
Bottle Diameter | Up to 85mm | Up to 85mm |
Bottle Height | Up to 200mm | Up to 200mm |
Fill Volume | 5gms. To 70gms. in Single Dose with the help of change parts for different fill volume | 5gms. To 70gms. in Single Dose with the help of change parts for different fill volume |
Fill Accuracy | ± 2% Depending upon the Powder, under the controlled level of Humidity | ± 2% Depending upon the Powder, under the controlled level of Humidity |
Humidity | Below 28% Rh required on machine to be arrange by customer | Below 28% Rh required on machine to be arrange by customer |
Power | 2.0 H.P. For Machine and 3.0 H.P. For Vacuum Pump | 2.5 H.P. For Machine and 3.0 H.P. For Vacuum Pump |
Overall Dimension | 1700 mm (L) x 1000 mm (W) x 1800 mm approx. | 2000 mm (L) x 1200 mm (W) x 1800 mm approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
Based on industry-standard models, here’s a breakdown of common features:
The machine is available in two models:
Fill volume ranges from 5gms to 70gms per dose (with change parts). Filling accuracy is ±2%, depending on powder characteristics when operated under controlled humidity below 28% RH.
It is ideal for sterile dry injectable powders, dry syrups, antibiotics, and other semi-free-flowing or non-free-flowing pharmaceutical powders. It handles bottles with diameters up to 85mm and heights up to 200mm. All product contact parts are SS316 (with Nylon/HDPE options) for hygiene and easy sterilization.
These features ensure high efficiency, sterility, and minimal downtime.
Humidity control below 28% RH is critical for maintaining filling accuracy and preventing powder clumping or bridging, especially with moisture-sensitive dry injectables. The machine is cGMP-compliant. Maintenance is user-friendly with easily removable contact parts for cleaning and sterilization. Regular tasks include cleaning the auger, vibratory funnel, and hopper, along with checking sensors and safety systems. Quick tool-less adjustments help minimize production downtime.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.
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