Low Speed Ampoule Filler

Q: Why should I choose a Low Speed Ampoule Filler over high-speed models?

The Low Speed Ampoule Filler is the best choice for small-scale production, R&D, clinical trials, or pilot plants because: It requires significantly lower investment Occupies very little space (ideal for cleanrooms) Offers excellent flexibility for different ampoule sizes with fast changeover Provides high filling accuracy and sterility at an affordable price Is easier to operate and maintain compared to high-speed lines It delivers professional, regulatory-compliant results without the complexity and cost of high-output equipment.

Description

Low Speed Ampoule Filler is a compact, versatile machine designed for small-scale production or laboratory use in the pharmaceutical, biotech, cosmetic, and chemical industries. It is used to fill and seal glass ampoules with liquid or, in some cases, powder, ensuring precision and compliance with cGMP standards. Its design prioritizes ease of use, minimal maintenance, and flexibility for various ampoule sizes, making it an excellent choice for startups, R&D, or low-volume production needs. For higher output, medium or high-speed fillers (e.g., four-head or eight-head models) would be more suitable.

Primarily used for filling and sealing open or closed glass ampoules (typically 1ml to 30ml) with injectable liquids, such as pharmaceuticals, vaccines, or cosmetic solutions.

Ideal for small-batch production, research and development (R&D), or pilot-scale operations where high output is not required.

Suitable for industries requiring sterile and accurate filling, such as pharmaceutical and biotech applications.

Built to meet cGMP, FDA, and EMA regulations, ensuring suitability for pharmaceutical production.

Often includes safety features like gas/oxygen safety valves, pressure reducers, and exhaust systems for safe operation.

Lower Output: Not suitable for large-scale production due to its limited speed (up to 50 ampoules/minute compared to 200–500 for high-speed models).

Manual Intervention: Some models may require manual loading or oversight, increasing labor compared to fully automated high-speed lines.

If you need specific details about a particular model, manufacturer, or additional features (e.g., integration with washing or labeling systems), please let me know.

Salient Features of Low Speed Ampoule Filler

Small footprint equipment.
1ml-30ml ampoule size suitability.
Frequency drive unit for speed variation.
IQ/OQ validation protocols on demand.
Acceptable error range of ± 1%.
Safety guards with guide railing on demand.

Class 100 Laminar Air Flow can be installed optionally.
Contact Area parts suitable for Autoclaving / Sterilization.
Monobloc design with filling and sealing units combined.
Different filling mechanism models available.
PLC system with Graphical User Interface in special models.

Working Principle of Low Speed Ampoule Filler

Machine having hopper for storing ampoules. User has to load empty ampoules on this hopper in bulk from where ampoule deliver onto moving rack one by one. In the movement over rack ampoule reaches to the filling station where filling needles fill preset volume of liquid in ampoules. Further ampoules reached to the sealing station where two burner nozzles installed in which first one is preheating nozzle and second is sealing nozzle. Rollers provided for rotation of ampoules, so evenly heating provided on all around the ampoule neck. During rotation of ampoule with nozzle gassing, the glass of ampoule get melt. Sealing clipper installed which do up & down movement above sealing unit. During down movement clipper take off excess melt part of ampoules and drop into waste glass collection box. Duly filled and packed ampoules get collected onto delivery tray of the machine.

Technical Specification of Low Speed Ampoule Filler

Model	AFS-30
Production Output	Up to 25 ampules/minute
Ampoule Size	1ml to 30ml
Filling Accuracy	± 1%
Require Gas for Sealing	LPG & Oxygen (O₂)
Nitrogen Flushing	Pre & Post Nitrogen Flushing Available
Power Specification	0.5 H. P.
Electrical Characteristics	230 Volts, Single Phase, 50 Hertz
Contact Parts	Made from Stainless Steel 316L.
Non-Contact Parts	Made from Stainless Steel 304
Overall Dimension	915mm (L) x 610mm (W) x 965mm (H) approx.
Net Weight	150 Kgs. approx.
Gross Weight	225 Kgs. approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Ampoule Filling Machine

Automatic Ampoule Filling Sealing Machine

Laboratory Ampoule Filling Sealing Machine

Closed Ampoule Filling Machine

Open Mouth Ampoule Filling Machine

Onion Skin Ampoule Filling Machine

Single Head Ampoule Filling Machine

Double Head Ampoule Filling Machine

Four Head Ampoule Filling Machine

Six Head Ampoule Filling Machine

Eight Head Ampoule Filling Machine

Applications of Ampoule Filling Machine

Advantages of Low Speed Ampoule Filler

Cost-Effective: Lower initial investment compared to high-speed models, making it ideal for startups or small-scale operations.

Flexibility: Handles a range of ampoule sizes (1ml to 30ml) with minimal changeover time.

Sterility and Safety: Ensures contamination-free filling with nitrogen flushing and hermetic sealing, meeting stringent pharmaceutical standards.

Ease of Operation: Requires minimal operator intervention, with semi-automatic or fully automatic options available.

Key Features of Low Speed Ampoule Filler

Compact Design: Low-speed ampoule fillers are designed to occupy minimal space, making them suitable for small facilities or labs.

Filling Capacity: Typically handles 15 to 50 ampoules per minute, depending on the model (e.g., single-head or two-head configurations). Filling volumes range from 0.5ml to 30ml in a single dose.

Material Construction: Contact parts are made of high-quality stainless steel 316L to prevent contamination, while non-contact parts are often stainless steel 304, ensuring durability and compliance with cGMP standards.

Filling Mechanism: Operates on a volumetric piston-pump or peristaltic pump system for precise liquid dosing, with neck-centering to ensure accurate filling without spillage.

Sealing Process: Uses combustible gases (oxygen and LPG/propane) for flame sealing, with pre-heating and sealing stations to ensure hermetic seals that protect contents from contamination.

Nitrogen Flushing: Equipped with pre- and post-nitrogen flushing to maintain sterility and prevent oxidation of sensitive products.

No Ampoule, No Fill System: Includes sensors to stop filling if no ampoule is detected, reducing waste and ensuring operational efficiency.

Ease of Maintenance: Features large openings for easy cleaning and tool-free changeover for different ampoule sizes, minimizing downtime.

FAQ for Low Speed Ampoule Filler

What is a Low Speed Ampoule Filler?

A Low Speed Ampoule Filler (Model AFS-30) is a compact, monobloc automatic machine designed for filling and flame sealing glass ampoules in small-scale production, R&D labs, pilot batches, or startup operations. It handles open-mouth glass ampoules ranging from 1ml to 30ml with high precision. The machine combines filling and sealing in one unit, making it ideal for low-volume pharmaceutical, biotech, cosmetic, and chemical applications where high-speed machines are unnecessary or too costly.

What is the production speed and filling capacity of the Low Speed Ampoule Filler?

The Low Speed Ampoule Filler typically delivers an output of up to 25–50 ampoules per minute (depending on ampoule size, fill volume, and configuration).

Filling range: 0.5 ml to 30 ml in a single dose
Filling accuracy: ±1% It uses volumetric piston pumps or peristaltic pumps with neck-centering for precise, drip-free filling. This makes it perfect for small-batch and laboratory-scale production rather than large commercial runs.

What industries and products is the Low Speed Ampoule Filler suitable for?

This machine is widely used in:

Pharmaceutical industry (injectables, vaccines, sterile liquids)
Biotechnology
Cosmetics (serums, essential oils)
Chemical industry

It is ideal for filling injectable liquids, diagnostic solutions, or other sterile products that require hermetic sealing to ensure long shelf life and protection from contamination.

What are the key features of your Low Speed Ampoule Filler?

Key features include:

Compact monobloc design with small footprint
Pre- and post-nitrogen flushing for oxidation protection
Flame sealing using LPG + Oxygen with pre-heating station
“No Ampoule – No Fill” and “No Ampoule – No Seal” sensors
Contact parts made of SS 316L (autoclavable)
Frequency drive for variable speed control
Easy and quick changeover with minimal parts
Optional Class 100 Laminar Air Flow and IQ/OQ documentation
cGMP, FDA, and EMA compliant construction

These features ensure high sterility, minimal product wastage, and ease of maintenance.

Why should I choose a Low Speed Ampoule Filler over high-speed models?

The Low Speed Ampoule Filler is the best choice for small-scale production, R&D, clinical trials, or pilot plants because:

It requires significantly lower investment
Occupies very little space (ideal for cleanrooms)
Offers excellent flexibility for different ampoule sizes with fast changeover
Provides high filling accuracy and sterility at an affordable price
Is easier to operate and maintain compared to high-speed lines

It delivers professional, regulatory-compliant results without the complexity and cost of high-output equipment.

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