Onion Skin Ampoule Filler

Onion Skin Ampoule Filler or onion skin ampoule filling Machine is suitable for filling onion skin ampoules. Machine designed to work with thin glass thickness onion skin tubes. These tubes are widely uses in biomedical industry for specific operations. Diameter and length of these tubes are lesser compared to standard pharmaceutical ampoules. Machine is suitable to fill 0.2ml to 5ml liquid into onion skin ampoules with precision liquid discharge system.

Onion skin ampoule filler machine having different machine models which can produce ampoules ranging from 25 ampoules per minute to 200 ampoules per minute. We have single head, double head, four head, six head and eight head machine models in this machine. We have option of different filling mechanism which includes peristaltic pump type filling, servo driven piston pump filling and mechanical piston pump filling. We can offer any of these as per user requirements.

Onion skin ampoules also called as biological indicators. Glass of these type of packing is kept thin, so that end user can easily break the ampoule during usage of product. As thickness of these ampoules is less, so it is also called as crushable glass ampoules. Sturdy design, easy operation and economical price are the key aspects which put Adinath in elite league of onion skin ampoule filling machine manufacturers in India.

Onion Skin Ampoule Filler Video

Key Features and Design:

• Purpose and Applications: The machine is engineered to fill and seal onion skin ampoules, which are commonly used for packaging agro-insecticides, veterinary medicines, cosmetics, and chemicals. It is also suitable for biological indicator tubes used in specific biomedical applications, such as mobile detection systems where ampoules are crushed to mix chemicals with a swab for detecting residues.

• Construction: Built on a stainless steel square pipe frame (AISI SS 304 for non-contact parts and AISI SS 316L for contact parts), the machine is encased in stainless steel with a matte finish, ensuring durability, hygiene, and compliance with cGMP and FDA standards. A large bottom opening facilitates easy cleaning and maintenance.

• Filling Mechanism: Operates on a volumetric piston-pump or peristaltic pump system, achieving high precision (up to 1% accuracy) for filling volumes ranging from 0.2ml to 25ml in a single dose. Some models offer servo-driven or mechanical piston pump options for enhanced control.

• Sealing Process: Uses oxygen and LPG (propane) or oxyhydrogen gas (generated via water electrolysis, replacing traditional gas cylinders) for flame sealing. Specially designed burners accommodate thin glass (0.3mm–0.8mm), with pre-warming and rotation stations ensuring uniform sealing. Burned-off ampoule tips are clipped and ejected into a separate container.

• Output Capacity: Depending on the model (single, double, four, six, or eight-head), production rates range from 10 to 250 ampoules per minute.

• Ampoule Handling: Supports ampoules with a minimum diameter of 7mm and height of 55mm, with no upper limit for size, as machines can be customized. The slant travel design accommodates variations in ampoule neck dimensions, thickness, and ovality.

• Gas Flushing: Features nitrogen or argon flushing before and after filling to ensure product stability and sterility.v

• Automation and User-Friendly Design: Equipped with a synchronized star wheel and eccentric rack system, ampoules are fed from a hopper, transferred to a transport rack, and processed in batches (1/2/4/6/8 ampoules per stroke). The machine includes a “No Ampoule – No Filling” system, pre-heating stations, and a dead tray for upright collection of sealed ampoules. Format parts can be changed by hand without tools, and a pendant-type electrical control panel enhances operational ease.

• Compact Footprint: Designed for cleanroom integration with minimal maintenance and easy sterilization, reducing contamination risks.

Operational Process:

1. Loading: Sterilized ampoules are loaded into a slant hopper, then fed via a star wheel to a moving eccentric rack in batches (1/2/4/6/8 ampoules).

2. Pre-Gassing: Nitrogen or argon is flushed into the ampoules to create an inert environment.

3. Filling: Precise liquid volumes (0.2ml to 25ml) are dispensed using piston or peristaltic pumps.

4. Post-Gassing: Additional nitrogen/argon flushing occurs to maintain sterility.

5. Pre-Warming and Sealing: Ampoules are warmed at a low-pressure flame station, then rotated at the sealing station for uniform sealing. Special rollers ensure consistent sealing quality.

6. Collection: Sealed ampoules are automatically collected in an upright position on a dead tray for further processing.

Applications:

• Pharmaceuticals: Filling sterile injections and biological indicators.

• Biotech: Handling sensitive biological materials.

• Cosmetics and Chemicals: Packaging specialized liquids like agro-insecticides or cosmetic solutions.

• Veterinary: Producing ampoules for animal health products.

This description covers the core functionality, design, and applications of Onion Skin Ampoule Fillers, ensuring a comprehensive understanding of their role in precise and sterile liquid packaging. For further details or specific models, you may refer to manufacturers like Adinath International.

Types of Ampoule Fillers

• Small Ampoule Filler
• Ampoule Filler and Sealer
• Onion Skin Ampoule Filler
• Servo Driven Ampoule Filler
• Peristaltic Pump type Ampoule Filler
• Closed Ampoule Filler
• Single Head Ampoule Filler
• Two Head Ampoule Filler
• Four Head Ampoule Filler
• Six Head Ampoule Filler
• Eight Head Ampoule Filler

Salient Features of Onion Skin Ampoule Filler

• Compact model.
• All contact parts made from high quality Stainless Steel 316 & other Non-contact parts made from Stainless Steel 304.
• “No Ampoule – No Filling” system.
• Ampoule neck centering during gas flushing and filling operations.
• Possibility of nitrogen gas flushing before, during and after filling.
• Full accessibility allows easy maintenance.
• Machine equipped with pre-warming station.
• Minimum change over time, little maintenance & easy cleaning.

Process Operation of Onion Skin Ampoule Filler

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules, one by one on moving eccentric ampoule rack in single/double/four/six/eight. During the movement of ampoule machine perform below mentioned operations:

1. Pre-gassing with Nitrogen
2. Filling the product
3. Post Gassing with Nitrogen
4. Pre-heating with LPG & Oxygen combination
5. Sealing with LPG & Oxygen combination

At the end duly filled and sealed ampoules get collected automatically onto collection tray of the machine. Ampoules now can be collected for further inspection and/or sticker labeling operations.

Technical Specification of Onion Skin Ampoule Filler

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.