An Automatic Ampoule Washer is a specialized pharmaceutical machine designed to clean and sterilize the internal and external surfaces of ampoules (small sealed glass containers) before filling with pharmaceuticals, medical solutions, or other liquids. These machines ensure compliance with Good Manufacturing Practices (cGMP) by minimizing contamination risks and maintaining sterility, which is critical for pharmaceutical, veterinary, and biotech industries.
The Automatic Ampoule Washer is engineered to wash ampoules with minimal contact between machine parts and the containers to prevent contamination. It typically features a gripper system that holds ampoules by the neck, inverts them for cleaning, and returns them to an upright position after washing. The machine is designed to handle a range of ampoule sizes (commonly 1ml to 20ml) with the use of interchangeable parts, ensuring versatility for different production needs. It employs a combination of water and air jets to thoroughly clean both the internal and external surfaces of ampoules, removing impurities, dust, and microbes to ensure sterility.
The Automatic Ampoule Washer is a critical component in pharmaceutical manufacturing, ensuring ampoules are sterile and free of contaminants before filling. Its advanced gripper system, customizable washing cycles, and compliance with cGMP standards make it an essential tool for maintaining product quality, safety, and regulatory compliance in high-throughput production environments.
Ampoules feed from the Infeed tray are received on an Infeed Feed worm then moves on Infeed starwheel. The Grippers picks up the Ampoule from Infeed Star Wheel and invert it in neck down position over washing needles and move along with the needle bar for Washing. Ampoules traveling in neck down position above washing needles and moves along with the Needle bar ensures maximum time for washing once the needle enter in the Ampoule neck. Machine having six different washing stations each of 6 needles for optimum Washing and the sequence can be adjusted as per requirements. Washer also having external wash for optimum washing of ampoules.
On completion of a cycle, washed Ampoules are again inverted to neck upward position and feed to output star wheel. Washed Ampoules received from output starwheel can be collected on Output Tray or can be pushed to tunnel. A separate pumping station (optional) gives the right quantum of water at the desired pressure. In the absent of separate pumping station, we can provide the re-circulation & siliconization system on request.
INTERNAL CLEANING:
The AVRW is equipped with 6 internal cleaning stations and each station has 6 cleaning needles making up a total of 36 cleaning needles. Each cleaning station is supplied via a pipe connected to the cleaning media-making washing area. This not only reduces the risk of particle generation, but also simplifies maintenance and cleaning efforts while saving time.
EXTERNAL CLEANING
The 3 external cleaning stations mounted in a stationary position above the ampoule can be easily adjusted for a specific height, angle and lateral position. Each cleaning station receives cleaning media-making through a pipe connected to the cleaning media-making washing area.
CLEANING MEDIA PRINCIPAL:
WFI, Purified water and air cleaning station are synchronized with the ampoule by reciprocating motion. Design is such that these media are put to use only when needles motion in forward direction. WFI consumption is further reduced by collecting the WFI in re-circulating water tank to be used later on in the pre-washing station.
Model | AVRW 120 | AVRW 240 |
Production Output | Up to 100 per minute | Up to 200 per minute |
Ampoule Diameter | 9mm to 21.5mm | 9mm to 21.5mm |
Ampoule Height | 60mm to 140mm | 60mm to 140mm |
Power Load | 4 H.P. | 5.5 H.P. |
Power Voltage | 440 Volts, 3 Phase 50 Hertz, 4 wire system | 440 Volts, 3 Phase 50 Hertz, 4 wire system. |
Optional Accessories |
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Utility |
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Water Tank & Pump | 3 nos. each with 25 liters Capacity & Centrifugal pump | 3 nos. each with 25 liters Capacity & Centrifugal pump |
Overall Dimension: | 2050mm (L) X 2000mm (W) X 1210mm (H) approx. | 2450mm (L) X 2000mm (W) X 1300mm (H) approx. |
Net Weight | 700 kgs. approx. | 900 kgs. approx. |
Gross Weight | 1000 kgs. approx. | 1300 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
1st wash | Recycled Water (WFI) |
2nd wash | Compressed Air |
3rd wash | DM Water |
4th wash | Compressed Air |
5th wash | Water for Injection (WFI) |
6th wash | Compressed Air |
We offer two models:
Both models are suitable for ampoules with diameters of 9mm to 21.5mm and heights of 60mm to 140mm. The output speed is adjustable, and the machine features low breakage rates with gentle neck-holding grippers.
Ampoules are loaded from an infeed tray onto a feed worm and transferred to an infeed starwheel. Grippers pick them up by the neck, invert them (neck down), and move them over washing needles. The machine performs 6 internal washing stations (with 36 needles total) and 3 external washing stations. A typical cycle includes 3 water washes and 3 air washes using independent circuits for recycled water, DM water, WFI, and compressed air. After washing, ampoules are re-inverted to an upright position and discharged via the output starwheel.
All product-contact parts and wash media parts are made from AISI 316L stainless steel, while non-contact parts use AISI 304 stainless steel and engineering plastics. The machine is a complete cGMP model with smooth finishes and welding as per pharmaceutical standards. It comes with IQ/OQ/DQ validation documentation and optional 21 CFR Part 11 compliant PLC & HMI systems with password protection and printing facility.
The machine requires:
It also supports 3 optional 25-liter water tanks with centrifugal pumps. A separate pumping station and recirculation system are available on request.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.
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