

Veterinary Powder Filling Machine For Vials are specialized pharmaceutical equipment designed to accurately dose sterile dry powders into glass vials under aseptic conditions. Powder Filling Machine are monoblock units that typically combine filling, rubber stoppering (bunging), and sometimes capping in a single platform to maintain sterility and efficiency. In the veterinary industry, they are used for packaging animal health products like penicillin for livestock, canine vaccines, or equine medications, where precision dosing and compliance with GMP standards are critical to ensure animal safety and regulatory approval. While most manufacturers produce versatile machines suitable for both human and veterinary applications, some explicitly highlight veterinary use. These systems handle vial sizes from 2ml to 100ml, with output speeds ranging from 30 to 600 vials per minute (VPM), depending on the model. Key technologies include vacuum-pressure dosing for repeatability, servo-driven wheels for precision, and in-process controls (IPC) like 100% weighing to minimize waste.
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The sterilized powder is stored in powder hopper is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density. The powder wheel having twelve ports which rotates at pre-determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel vacuum plate is provided. There is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked into the port of powder wheel during vacuum; according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade. Doctor blades can be adjusted from outside also without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the container. The time dose of Compressed air (Nitrogen Gas), sterilized low pressure air sequentially flushes out powder from the port of powder wheel in to the container one by one.
The filled containers are immediately separated on the conveyor by vial separator and moves further for stoppering operation.
The sterilized, siliconised, rubber stoppers stored in the vibrator bowl moves to vibratory bowl and stacked vertically in the rubber stopper chute. The container is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further container is passed between two pressing roller for tight fit fixing of rubber stoppers.
Models | APF 12S | APF 12D |
Production Output | Up to 100 vials/minute | Up to 200 vials/minute |
Fill Volume | 50 mg. to 10grams | 50 mg. to 10 grams |
Vial Size | 5ml to 250ml | 5ml to 250ml |
Filling Accuracy | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder |
Power Load | 3.5 H. P. | 4.5 H. P. |
Overall Dimension | 2600mm (L) X 1100mm (W) X 1800mm (H) approx. | 3000mm (L) X 1100mm (W) X 1800mm (H) approx. |
Net Weight | 500 kgs. approx. | 700 kgs. approx. |
Gross Weight | 750 kgs. approx. | 950 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The Veterinary Powder Filling Machine for Vials is a specialized aseptic monobloc system designed to accurately fill sterile dry powders into glass vials under controlled cleanroom conditions. It is widely used in the veterinary pharmaceutical industry for filling animal medications such as antibiotics (e.g., penicillin for livestock), vaccines, and other injectable powders, ensuring precise dosing, sterility, and compliance with cGMP standards for animal healthcare.
The machine is available in two models:
It supports fill volumes from 50 mg to 10 grams (up to 1500 mg in single dosing with change parts) and handles vial sizes from 5 ml to 250 ml.
The machine offers a filling accuracy of ±2% to ±3% depending on the powder characteristics, bulk density uniformity, and environmental conditions (especially humidity control). It uses a vacuum-driven powder wheel with mechanical agitators and servo motors for consistent and precise dosing.
This machine is ideal for veterinary use due to its high sterility assurance, precise dosing for animal-safe formulations, and full cGMP compliance. Maintenance is simplified with easy-to-remove contact parts, tool-less adjustments, and quick changeover for different vial sizes or powders, minimizing downtime while supporting fast cleaning and sterilization.
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