

Vial Filling Machine is a precision automated or semi-automated system designed for accurate, high-speed filling of liquid, semi-liquid, or powder pharmaceutical, biotech, and cosmetic products into glass or plastic vials. Vial Filling Machine are widely used in sterile and aseptic production environments to ensure product safety, dosage accuracy, and compliance with stringent regulatory standards.
The incoming dry vials (sterilized and siliconized) are fed through the unscrambler and suitably guided on the moving Delrin slat conveyor belt at the required speed of the correct placement below filling unit.
The filling unit consists of Filling Head, Syringes & Nozzles; Syringes & Nozzles are made of AISI SS 316L materials. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be increase & decrease by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid reaches to filling nozzles through silicon transparent pipe. Nozzles having up & down movement with help of cam mechanism, and it come down when vial hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers two vials together on conveyor for rubber stoppering operation.
Stoppering unit consist of Star wheel, Vibrator unit and Bowl. The sterilized and siliconized rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it picks up the rubber stopper from the exit end of the chute and rubber stopper pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.
Model | ALVF-40 | ALVF-80 | ALVF-120 | ALVF – 250 |
Filling Heads | Two | Four | Eight | Twelve |
Production Rate | Up to 40 Vials/Minute | Up to 80 Vials/Minute | Up to 150 Vials/Minute | Up to 250 Vials/Minute |
Vial Diameter | 15mm to 70mm | 15mm to 70mm | 15mm to 70mm | 15mm to 70mm |
Vial Height | 25mm to 140mm | 25mm to 140mm | 25mm to 140mm | 25mm to 140mm |
Filling Precision | ±1% | ±1% | ±1% | ±1% |
Power Required | 1 H.P. | 1.5 H.P. | 2 H.P. | 2 H.P. |
Electrical Characteristics | 440 Volts, 3 Phase, 50 Hertz | 440 Volts, 3 Phase, 50 Hertz | 440 Volts, 3 Phase, 50 Hertz | 440 Volts, 3 Phase, 50 Hertz |
Overall Dimension | 2050mm (L) x 850mm (W) x 1700mm (H) | 2200mm (L) x 850mm (W) x 1700mm (H) | 3000mm (L) x 945mm (W) x 1700mm (H) | 3500mm (L) x 945mm (W) x 1700mm (H) |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
A Vial Filling Machine is a precision-engineered automated or semi-automated system designed for accurate filling of liquid, semi-liquid, or powder products into glass or plastic vials. It is primarily used in the pharmaceutical, biotech, and cosmetic industries for sterile filling of injectables, vaccines, serums, and other parenteral products. The machine ensures high filling accuracy (±1%), maintains sterility under Laminar Air Flow (Class 100), and complies with cGMP and USFDA standards.
We offer four main models:
– ALVF-40 → Up to 40 vials/min (2 filling heads)
– ALVF-80 → Up to 80 vials/min (4 filling heads)
– ALVF-120 → Up to 150 vials/min (8 filling heads)
– ALVF-250 → Up to 250 vials/min (12 filling heads)
All models handle vial diameters from 15mm to 70mm, heights from 25mm to 140mm, and filling volumes from 2ml to 250ml. The actual output depends on vial size, liquid viscosity, and fill volume. Custom configurations (including monoblock with stoppering and capping) are also available.
The machine uses a volumetric piston filling system with SS 316L syringes and nozzles, along with non-return valves for consistent dosage. It features a “No Vial – No Filling” sensor and “No Vial – Machine Stop” system to avoid wastage and cross-contamination. All product contact parts are made of Stainless Steel 316L, and the machine operates under Laminar Air Flow in a Class 100 environment. Optional nitrogen flushing is available to extend product shelf life. Filling accuracy is maintained at ±1% or better.
Sterilized vials are fed via an in-feed turntable or unscrambler onto a Delrin slat conveyor. They are positioned under the filling heads by a star wheel. The SS 316L syringes draw the product and dispense it precisely into the vials through nozzles that move up and down via a cam mechanism. After filling, vials move to the stoppering unit where sterilized rubber stoppers are automatically placed and pressed. The entire process is continuous, with sensors ensuring smooth, contamination-free operation. The machine can be integrated with washing, sterilizing, and sealing units for a complete line.
Key features include:
– Variable AC frequency drive for speed control
– Digital vial counter
– PLC with HMI (optional)
– Easy changeover and low maintenance
– IQ/OQ documentation support
– Compact monoblock design
Benefits: High-speed production with excellent accuracy, enhanced sterility, minimal product wastage, regulatory compliance, quick validation, and space efficiency. It reduces contamination risk, lowers operational costs, and is ideal for both small-batch and large-scale production.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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