Rotary Vial Washing Machine

Description

Rotary Vial Washing Machine is a high-speed, fully automatic pharmaceutical equipment designed for external and internal cleaning of glass vials (typically 2 ml to 100 ml) used in injectable formulations. It ensures thorough removal of particulate matter, pyrogens, and contaminants through a continuous rotary motion, making it ideal for sterile pharmaceutical production lines.

  • Construction: Typically made from stainless steel (SS 316L for contact parts) for durability, corrosion resistance, and easy sterilization. Machines often include acrylic covers for visibility during operation and safety interlocks that stop the process if the cover is lifted.

 

  • Washing Mechanism:
    • Vials are fed via an infeed turntable or conveyor and gripped by the neck (in rotary models) or indexed into pockets (in linear models) to invert them for gravity-assisted cleaning.
    • High-pressure jets from multiple washing needles deliver sequential rinses: pre-wash, detergent wash, recycled rinses, and final purified water rinse. This ensures both internal and external cleaning with minimal water usage.
    • External washing arms or jets target the vial body for comprehensive decontamination.

 

  • Automation and Controls: Equipped with PLC and HMI for precise control, optional AC drives for speed adjustment, and pneumatic components for reliable handling. Some models support RABS for enhanced sterility.

If you need details on specific models and pricing. let me know!

Working Principle of Rotary Vial Washing Machine

Vials feed from the Infeed turn table / tray are received on Infeed Star wheel / Feed worm then moves on Infeed starwheel. The Grippers picks up the vial from Infeed Star Wheel and invert it in neck down position over washing needles and move along with the needle bar for Washing. Vials traveling in neck down position above washing needles and moves along with the Needle bar ensures maximum time for washing once the needle enter in the vial neck. Machine having six different washing stations each of 6 needles for optimum Washing and the sequence can be adjusted as per requirements. Washer also having external wash for optimum washing of vials. On completion of a cycle, washed vials are again inverted to neck upward position and feed to output star wheel. Washed vials received from output starwheel can be collected on Output Tray or can be pushed to tunnel. A separate pumping station (optional) gives the right quantum of water at the desired pressure. In the absent of separate pumping station, we can provide the re-circulation & siliconization system on request.

 

INTERNAL CLEANING:

The AVRW is equipped with 6 internal cleaning stations and each station has 6 cleaning needles making up a total of 36 cleaning needles. Each cleaning station is supplied via a pipe connected to the cleaning media-making washing area. This not only reduces the risk of particle generation, but also simplifies maintenance and cleaning efforts while saving time.

 

EXTERNAL CLEANING

The 3 external cleaning stations mounted in a stationary position above the ampoule can be easily adjusted for a specific height, angle and lateral position. Each cleaning station receives cleaning media-making through a pipe connected to the cleaning media-making washing area.

 

CLEANING MEDIA PRINCIPAL:

WFI, Purified water and air cleaning station are synchronized with the ampoule by reciprocating motion. Design is such that these media are put to use only when needles motion in forward direction. WFI consumption is further reduced by collecting the WFI in re-circulating water tank to be used later on in the pre-washing station.

Technical Specification of Rotary Vial Washing Machine

Models

AI-DPM 12

AI-DPM 16

Production Output

Up to 80 bottles/minute

Up to 120 bottles/minute

Bottle Diameter

Up to 85mm

Up to 85mm

Bottle Height

Up to 200mm

Up to 200mm

Fill Volume

5gms. To 70gms. in Single Dose with the help of change parts for different fill volume

5gms. To 70gms. in Single Dose with the help of change parts for different fill volume

Fill Accuracy

± 2% Depending upon the Powder, under the controlled level of Humidity

± 2% Depending upon the Powder, under the controlled level of Humidity

Humidity

Below 28% Rh required on machine to be arrange by customer

Below 28% Rh required on machine to be arrange by customer

Power

2.0 H.P. For Machine and 3.0 H.P. For Vacuum Pump

2.5 H.P. For Machine and 3.0 H.P. For Vacuum Pump

Overall Dimension

1700 mm (L) x 1000 mm (W) x 1800 mm approx.

2000 mm (L) x 1200 mm (W) x 1800 mm approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Vial Washing Machine

Applications of Vial Washing Machine

Key Features of Rotary Vial Washing Machine

Continuous Rotary Operation: Vials are indexed through multiple washing stations in a circular path, ensuring high output.

Needle-Based Cleaning: Diving needles enter each vial for precise internal jet washing; external washing via fixed or rotary sprays.

Cost-Effectiveness: Recycles rinse water to minimize consumption; compact footprint for cleanroom compatibility.

GMP Compliance: Complete SS 304/316 construction, mirror-polished contact parts, acrylic or toughened glass enclosure, and easy-clean design.

PLC + HMI Controlled: Fully automated with recipe management, fault alarms, and data logging.

Aseptic Design: Suitable for cleanroom installation.

Washing Cycle of Rotary Vial Washing Machine

1st wash           

Recycled Water (WFI)

2nd wash

Compressed Air

3rd wash          

DM Water

4th wash

Compressed Air

5th wash

Water for Injection (WFI)

6th wash

Compressed Air

FAQ for Rotary Vial Washing Machine

The machine offers high output with production capacity up to 200 vials per minute, depending on the model and vial size. It features a digital speed indicator for real-time output monitoring and is suitable for both standalone and inline operation in high-speed filling lines.

The machine is suitable for glass vials ranging from 2 ml to 100 ml. It uses a gripper-based system that inverts the vials for effective neck-down washing, providing flexibility across different vial sizes commonly used in injectable formulations.

Key features include:

  • Complete cGMP compliant design with SS 316L contact parts
  • 6 internal washing zones with 36 needles (18 jets for internal washing)
  • 3 Water washes + 3 Air washes with independent circuits
  • PLC + HMI control system (with optional 21 CFR Part 11 compliance)
  • Adjustable washing sequence as per user requirements
  • Automatic Infeed and Exit with safety interlocks
  • Low water consumption with recycling options

The standard washing cycle includes 6 stations:

  1. Recycled Water (WFI)
  2. Compressed Air
  3. DM Water / Purified Water
  4. Compressed Air
  5. Water for Injection (WFI) – Final Rinse
  6. Compressed Air – Final Drying

Both internal and external washing are performed for optimal cleanliness.

Countries We Export to

United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba

Partner with Industry Experts

Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.

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