Multijet Ampoule Washing Machine

Q: What is the production capacity and output of the Multijet Ampoule Washing Machine?

The machine supports manual loading and unloading with automatic PLC-controlled washing cycles. Output depends on the needle plate (jet holes) and operator efficiency: 56-hole plate: ~1,680 containers/hour 99-hole plate: ~2,970 containers/hour 189-hole plate: ~5,670 containers/hour 240-hole plate: ~7,200 containers/hour 340-hole plate: ~10,200 containers/hour It can achieve up to 100 ampoules/vials per minute (approx. 30 trays per hour) depending on container size and tray configuration.

Description

In the highly regulated pharmaceutical industry, maintaining impeccable cleanliness and sterility is paramount, especially for injectable products. A Multijet Ampoule Washing Machine stands out as a reliable, semi-automatic, compact, and versatile piece of pharmaceutical equipment specifically designed to clean glass ampoules and vials effectively. This advanced ampoule washer ensures full compliance with current Good Manufacturing Practices (cGMP) standards, making it an essential asset for injectable manufacturing facilities worldwide.

Also known as a multi-jet ampoule washer or vial washing machine, this equipment uses high-pressure multijet technology to deliver powerful, targeted sprays of water and air inside and outside the containers. It thoroughly removes dust, particles, residues, and contaminants from glass ampoules and vials, preparing them for filling, sealing, and sterilization processes.

The machine is particularly popular in small to medium-scale injectable manufacturing units due to its user-friendly design and flexibility. With interchangeable change parts, it efficiently handles a wide range of sizes: ampoules from 1ml to 20ml and glass vials from 2ml to 100ml. This adaptability eliminates the need for multiple dedicated machines, saving space and investment costs.

Salient Features of Multijet Ampoule Washing Machine

Compact GMP model.
Solenoid valve system with timer operated mechanism controlled from HMI.
PLC HMI based touch screen control panel.
Suitable to wash 1ml to 20ml ampoules and 2ml to 100ml vials.
Both internal & external washing ensuring absolutely & continuous ampoule after sequential washing.
Acrylic top cover provided for clear view of washing during running of the machine.
IQ/OQ documentation can be provided.

On-line poly carbonates housing with P.P. replaceable filter cartridge of 5 or 10 micron of water for best possible washing.
All contact parts of washing media & Compressed Air are made from Stainless Steel316 or Polycarbonate HDPE or P.P. or any other FDA approved material.
Easy to operate machine can be operated by even semi-skilled operator.
Positive & pressurized jets through washing needle for pressure cleaning at minimum usages for washing media. Sound design concept of pressure tank for reverse & continuous supply of wash medias.
Machine automatically stop in case of acrylic top cover lifted during cycle operation and machine re-start from the point when cover is pushed down.

Working Principle of Multijet Ampoule Washing Machine

Ampoules are loaded in bulk onto combi tray if received in ready to dump boxes, which will have exactly same number of Ampoules and the pitch, as loading tray. Alternatively, each Ampoule/Vial has to be arranged into the tray individually. The loading tray is placed directly into the machine & the handlebar is lowered for automatic centering of washing needles into the Ampoules neck. The top cover is lowered & switch is operated for automatic sequential washing. Washing is performed from inside and outside of each individual Ampoule. Machine automatically stops after one complete washing cycle with buzzer sound and red-light indication. For removal of tray, reverse procedure is to be observed. Depending on loading & operator’s efficiency one can achieve 30 loading trays in an hour.

Multijet Ampoule and Vial Washing Machine is valued for its robust design, ease of operation (even by semi-skilled operators), and ability to deliver sterile, contaminant-free ampoules and vials, critical for pharmaceutical filling processes.

Technical Specification of Multijet Ampoule Washing Machine

Model	AAVW 340P
Loading & Unloading	Manually
Washing Process	Automatic through PLC
Input Specification	2ml to 100ml vials and 1ml to 20ml ampoules
Production Output	Up to 100 ampoules/vials per minute(depends upon needle plate and operator’s efficiency)
Power Supply:	0.25 H.P.
Electrical Characteristics:	220 Volts, Single Phase, 50 Hertz
Net Weight:	120 Kgs. Approx.
Gross Weight:	250 Kgs. Approx
Net Dimension:	1200 mm (L) X 1020 mm (W) X 1080 mm (H) approx.
Case Dimensions:	1350 mm (L) X 1200 mm (W) X 1280 mm (H) approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Ampoule Washing Machine

Ampoule Vial Washing Machine

Automatic Ampoule Washer

Automatic Rotary Ampoule Washing Machine

Automatic External Ampoule Washing Machine

High speed Ampoule Washing Machine

Lab Scale Ampoule Washing Machine

Multijet Ampoule Washing Machine

Linear Ampoule Washing Machine

Applications of Ampoule Washing Machine

Advantages of Multijet Ampoule Washing Machine

Dual internal and external water/air washing removes all particles and residues.

Solenoid valves spray only when ampoules are detected, saving water and air.

Continuous automated operation matches high-capacity packaging lines.

Built with AISI 316L stainless steel contact parts for sterile operation.

Targeted jet nozzles prevent cross-contamination between batches.

Tool-less adjustment parts allow fast switching between ampoule sizes.

Smooth starwheel and worm-screw feeding connects easily with upstream and downstream equipment.

Washing Cycle of Multijet Ampoule Washing Machine

Internal/External Washing	Washing Media
1st Wash	De-Mineralized Water
2nd Wash	Purified Air
3rd Wash	De-Mineralized Water
4th Wash	Purified Air
5th Wash	Water for Injection
6th Wash	Purified Air

Key Features of Multijet Ampoule Washing Machine

Construction: Built with stainless steel (AISI 316L for contact parts and AISI 304 for non-contact parts) or FDA-approved materials like polycarbonate, HDPE, or PP, ensuring durability, corrosion resistance, and compliance with sterile processing requirements.

Washing Mechanism: Utilizes positive and pressurized jets through washing needles for thorough internal and external cleaning, minimizing the use of washing media (e.g., purified water, distilled water, or compressed air). The machine typically performs six washing cycles, which can include combinations of water and air washes, customizable based on user needs.

Operation: Features a mechanical motorized cam-operated valve system as standard, with optional timer-operated solenoid valves or microprocessor-controlled sequences for precise control. The washing cycle time is adjustable, and the process is managed via a PLC-based HMI touch screen control panel in advanced models.

Loading and Unloading: Ampoules or vials are loaded onto combi trays (made of cast nylon with varying hole counts, e.g., 53, 100, 189, 240, or 340, depending on container size). Trays can be loaded in bulk if received in ready-to-dump boxes or arranged manually. The tray is placed in the machine, and a handlebar ensures automatic centering of washing needles into the container mouths.

Safety and Visibility: Equipped with an acrylic top cover for clear observation of the washing process. The machine automatically stops if the cover is lifted during operation and resumes from the same point when closed, enhancing operator safety.

Efficiency: Capable of processing up to 30 trays per hour, depending on operator efficiency and loading speed, with a production capacity of 3,000 to 12,960 ampoules/vials per hour, depending on the model.

Additional Features:
- A pressure tank ensures a continuous and reverse supply of washing media.
- Includes an online polycarbonate housing with a replaceable 5 or 10-micron PP filter cartridge for optimal water purity.
- Overload clutch to prevent jamming and optional pressure regulator with a pressure switch for enhanced control.
- IQ/OQ documentation is available for validation purposes.

Applications: Ideal for pharmaceutical industries, research institutions, and pilot-scale production where sterile and clean containers are critical for injectable drugs.

Production Performance of Multijet Ampoule Washing Machine

Jet Needles	Production Output
56 Holes Plate	1680 per hour approx. (56 holes plate x 30 cycles)
99 Holes Plate	2970 per hour approx. (56 holes plate x 30 cycles)
189 Holes Plate	5670 per hour approx. (56 holes plate x 30 cycles)
240 Holes Plate	7200 per hour approx. (56 holes plate x 30 cycles)
340 Holes Plate	10200 per hour approx. (56 holes plate x 30 cycles)

FAQ for Multijet Ampoule Washing Machine

What is a Multijet Ampoule Washing Machine and for which production scale is it ideal?

The Multijet Ampoule Washing Machine (Model AAVW 340P) is a semi-automatic, compact cGMP-compliant washer designed for thorough internal and external cleaning of glass ampoules (1ml to 20ml) and glass vials (2ml to 100ml) using interchangeable change parts. It is best suited for small to medium-scale injectable, pharmaceutical, biotech, veterinary, and cosmetic manufacturing units. The machine uses a multi-jet needle system with pressurized washing media and is easy to operate even by semi-skilled operators.

What is the production capacity and output of the Multijet Ampoule Washing Machine?

The machine supports manual loading and unloading with automatic PLC-controlled washing cycles. Output depends on the needle plate (jet holes) and operator efficiency:

56-hole plate: ~1,680 containers/hour
99-hole plate: ~2,970 containers/hour
189-hole plate: ~5,670 containers/hour
240-hole plate: ~7,200 containers/hour
340-hole plate: ~10,200 containers/hour

It can achieve up to 100 ampoules/vials per minute (approx. 30 trays per hour) depending on container size and tray configuration.

How does the washing process work in the Multijet Ampoule Washing Machine?

Containers are arranged in combi trays and placed in the machine. A handlebar lowers to center the washing needles automatically. The acrylic top cover is closed, and the cycle starts via the PLC HMI panel. It performs six sequential washing stages:

DM Water
Purified Air
DM Water
Purified Air
Water for Injection (WFI)
Purified Air

Positive pressurized jets clean both inside and outside the containers. The machine stops automatically with a buzzer and indicator light after one complete cycle. Independent circuits minimize cross-contamination, and media usage is kept low due to high-pressure jets.

What materials and compliance standards does the Multijet Ampoule Washing Machine follow?

All contact parts with washing media are made of AISI 316L Stainless Steel, FDA-approved materials, Polycarbonate, or PP. Non-contact parts use AISI 304 Stainless Steel and engineering plastics. The machine is a complete cGMP model with smooth finishes, solenoid valve system, pressure tank for continuous media supply, and an on-line 5/10 micron filter. It comes with IQ/OQ documentation and supports optional 21 CFR Part 11 compliant PLC + HMI validation for regulatory requirements.

What are the key features and optional accessories available?

Key features include:

PLC + HMI touch screen control for easy operation and customizable wash times
Acrylic top cover with safety interlock (machine stops if cover is lifted)
Minimal washing media consumption with efficient pressurized jets
Overload clutch protection and low power consumption (0.25 H.P., 220V Single Phase)
Compact footprint and easy changeover for different sizes

Optional accessories:

Separate pumping station with 3 pumps & 3 × 25L tanks
Recirculation and siliconization system
Printing facility
Password protection and safety cabinet

Multijet Ampoule Washing Machine

Description

Salient Features of Multijet Ampoule Washing Machine

Working Principle of Multijet Ampoule Washing Machine

Technical Specification of Multijet Ampoule Washing Machine

Types of Ampoule Washing Machine

Lab Scale Ampoule Washing Machine

Applications of Ampoule Washing Machine

Advantages of Multijet Ampoule Washing Machine

Dual internal and external water/air washing removes all particles and residues.

Solenoid valves spray only when ampoules are detected, saving water and air.

Continuous automated operation matches high-capacity packaging lines.

Built with AISI 316L stainless steel contact parts for sterile operation.

Targeted jet nozzles prevent cross-contamination between batches.

Tool-less adjustment parts allow fast switching between ampoule sizes.

Smooth starwheel and worm-screw feeding connects easily with upstream and downstream equipment.

Washing Cycle of Multijet Ampoule Washing Machine

Key Features of Multijet Ampoule Washing Machine

Production Performance of Multijet Ampoule Washing Machine

FAQ for Multijet Ampoule Washing Machine

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