Pharmaceutical Double Cone Blender

A Pharmaceutical Double Cone Blender is a specialized tumbling mixer used for uniformly blending dry powders and granules in pharmaceutical manufacturing, ensuring consistent mixtures for tablets, capsules, and other dosage forms. Its double-cone design, with two conical sections joined at a central cylindrical shell, facilitates efficient mixing through diffusion and tumbling as the vessel rotates on a horizontal axis.

Pharmaceutical Double Cone Blender Video

Key Features

• Material: Stainless steel contact parts ensure corrosion resistance and cGMP compliance for contamination-free processing.

• Design: Wide loading aperture and butterfly/slide valve for dust-free charging and discharge; slant design aids complete emptying.

• Operation: Rotates at 8-25 RPM, driven by a motor with a balanced cone to minimize gearbox strain.

• Add-ons: Intensifier bars, baffles, vacuum loading, or jackets for heating/cooling.

Working Mechanism

Materials are loaded through the top, and rotation causes powders to tumble and cascade, mixing via diffusion. The process takes 5-15 minutes, achieving up to 99% uniformity, ideal for free-flowing solids with low liquid content (<10%) and specific gravity <7 g/cm³.

Applications

• Pharmaceuticals: Blending APIs, excipients, and granules for uniform formulations.

• Other industries: Food, chemicals, and cosmetics for dry mixing.

Advantages

• High uniformity with low shear, preserving fragile particles.

• Easy to clean, operate, and scale; energy-efficient and GMP-compliant.

Limitations

• Ineffective for very fine or cohesive powders without intensifiers; limited for wet mixing or high-shear needs.

Salient Features of Double Cone Mixer

• Compact GMP Model.

• No Bottle – No Fill System

• Rotary Bottle Movement System with Rotary Funnel System

• Funnel with Unique Vibratory system for filling semi free flow powder at higher speed.

• All contact parts with easy removal system for Cleaning / AutoClaving / Sterilization.

• Machine construction in SS304 material.

• Filling Accuracy of ±2% depending on powder at controlled humidity below 28% Rh.

• Automatic Infeed and Exit of Bottles through Star Wheel System.

• No Bottle at infeed conveyor – Automatic Machine on/off system.

• Tool Less adjustment of Doctor Blade and Wiper Blade saves valuable time and easy for setting.

• Low Air – Machine Stop System.

• Low Vacuum – Machine Stop System.

• Toughened Glass Safety Cabinet.

Process Operation of Double Cone Blender

The Double shape blenders have long two corner of product container for more rubbing and tumbler effect to the material for fast and homogenizing mixing. It can perform homogenously dry mixing of free-flowing powders, granules requiring low shearing force, Mixing and Blending of particles with rapid intermixing of particles irrespective of varying specific gravities. The material is loaded into the double cone blender drum. The double blender is tumbles the material in the container and spread out. The mixing is achieved in 5 to 15 minutes with better homogeneity.

Technical Specification of Double Cone Blender

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.