Two Head Ampoule Filling Machine

A Two Head Ampoule Filling Machine is a compact, automated device designed for precision filling and sealing of glass ampoules, primarily used in pharmaceutical, biotech, cosmetic, and chemical industries. Built on the principle of slant travel for ampoules, it accommodates variations in neck dimensions and thicknesses, ensuring reliable performance.

Two Head Ampoule Filling Machine Video

Key Features:

• Construction: Made with a stainless steel (SS) square pipe frame and SS 316L contact parts for durability and compliance with cGMP standards. Non-contact parts are typically SS 304, with a matte finish for aesthetic appeal and ease of cleaning.

• Filling Capacity: Suitable for filling 1ml to 25ml ampoules, with a dosing range of 0.5ml to 25ml per cycle. It operates using volumetric piston pumps, servo-driven pumps, or peristaltic pumps, depending on customization.

• Output: Capable of filling 30 to 90 ampoules per minute (approximately 1,800 to 5,400 ampoules per hour), ideal for small to medium-scale production.

• Operation: Fully automatic with minimal human intervention. Ampoules are loaded into an in-feed hopper, transferred via a synchronized star wheel to a transport rack, and moved through sequential stations:

  • Pre-Nitrogen Flushing: Inert gas (nitrogen) is flushed to reduce oxygen exposure.

  • Filling: Two filling heads discharge precise liquid volumes, with neck centering for accuracy.

  • Post-Nitrogen Flushing: Additional nitrogen flush to maintain sterility.

  • Pre-Heating: A low-pressure flame warms ampoules for sealing.

  • Sealing: Uses oxygen and LPG (propane) with specially designed rollers for uniform sealing of open or closed-type ampoules (Type B and C).

• Sealing Process: Features a two-stage sealing system (pre-heating and final sealing) to ensure clean, precise seals. Waste tips are collected in a high-quality SS container.

• Flexibility: Minimal changeover parts required for different ampoule sizes (1ml to 20ml or 30ml, depending on the model). Format parts can be changed by hand without tools.

• Control System: Equipped with a user-friendly touchscreen interface for adjusting fill volume, speed, and sealing temperature. Some models include PLC-based controls for automated fill volume adjustments and an automatic stop function to prevent accidents and reduce wastage.

• Maintenance: Designed for low maintenance with easy-clean features, including a large bottom opening for access. Stainless steel construction ensures corrosion resistance and sterility.

• Safety and Compliance: Complies with GMP and CE standards. Optional safety cabinets, laminar airflow, or isolators can be integrated for sterile Class 100 filling. Energy-saving features, such as automatic shut-off when idle, reduce operational costs.

• Additional Features:

  • Dead tray for upright ampoule collection.

  • Pre-warming station for thick glass ampoules to ensure perfect sealing.

  • Adjustable ampoule loading tray for handling various sizes.

  • Optional servo-driven or peristaltic pump for enhanced precision and sterility.

Applications:

• Pharmaceuticals: Filling sterile injectables, vaccines, and other liquid medications.

• Cosmetics: Packaging serums and other liquid products (e.g., 2ml ampoules for cosmetic serums).

• Biotech and Veterinary: Filling specialized solutions.

• Chemicals: Handling agro-insecticides and other chemical formulations.

Benefits:

• High precision and efficiency with minimal product loss.

• Compact design requiring less floor space, ideal for small to medium-scale facilities.

• Customizable filling mechanisms (piston, servo, or peristaltic) to meet specific needs.

• Robust, durable construction for long-term use with minimal upkeep.

• Energy-efficient with automated features to streamline production.

Types of Ampoule Filling Machines

• Small Ampoule Filling Machine
• Ampoule Filling and Sealing Machine
• Onion Skin Ampoule Filling Machine
• Servo Driven Ampoule Filling Machine
• Peristaltic Pump type Ampoule Filling Machine
• Closed Ampoule Filling Machine
• Single Head Ampoule Filling Machine
• Two Head Ampoule Filling Machine
• Four Head Ampoule Filling Machine
• Six Head Ampoule Filling Machine
• Eight Head Ampoule Filling Machine

Salient Features of Two Head Ampoule Filling Machine

• Compact cGMP model.

• Higher output up to 3000 Ampoules per hour.

• All contact parts made from High Quality Stainless Steel 316L & Non-contact parts made from Stainless Steel 304.

• Minimum change over parts from 1ml to 10ml ampoule size.

• “No Ampoule – No Filling” system.

• Ampoule neck centering during gas flushing and filling operations.

• Possibility of nitrogen gas flushing before, during and after filling.

• Full accessibility allows easy maintenance.

• Machine equipped with pre-warming station.

• Flow Meters for regulating flames easily.

• Minimum change over time, little maintenance, easy cleaning.

Process Operation of Two Head Ampoule Filling Machine

Empty washed & sterilized ampoules receive automatically on wire mesh conveyor belt from outfeed of sterilizing tunnel. Ampoule fed automatically into in-feed hopper from the left hand side of the machine and feed to receiving rack through cassette. The moving rack which moves horizontally collect two ampoules from the receiving rack and transfer the ampoule to the machine in left to right in an inclined position through pre-gassing. Pre-gassing, Filling, Post Gassing, Pre-heating & sealing sta.

Technical Specification of Two Head Ampoule Filler

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.