Industrial EO Gas Sterilizer

Description

In the challenging fields of healthcare, pharmaceuticals, and precision manufacturing, ensuring complete sterility is essential. An EO Sterilizer Machine, also referred to as an Ethylene Oxide Sterilizer, is one of the most reliable and adaptable options for sterilizing items that cannot withstand high heat or moisture. Unlike conventional steam autoclaves or dry heat ovens, EO sterilization works at lower temperatures, making it the preferred choice for delicate, intricate, and heat-sensitive materials. An Ethylene Oxide (EO) Sterilizer is a specialized system that uses EO gas, a strong alkylating agent, to kill bacteria, viruses, fungi, and spores.

 

The gas can reach deep into packaging, device channels, and porous surfaces, interfering with the DNA and proteins of microorganisms. This process achieves a very high Sterility Assurance Level (SAL) of 10⁻⁶, which means the chance of any single microorganism surviving is one in a million.

 

EO sterilization typically takes place at controlled low temperatures, ranging from 80 to 150°F (27 to 66°C), with carefully managed humidity and vacuum or pressure cycles. This careful method ensures that sensitive medical equipment remains intact while still satisfying strict regulatory requirements from organizations such as the FDA, ISO 11135, and AAMI.

Working Principle of Industrial EO Gas Sterilizer

  • Low-Temperature & Moisture-Free Cycle: Functions as a cool, dry alternative operating around 50°C, safeguarding temperature-sensitive goods from thermal degradation.

 

  • Superior Diffusion & Reach: Possesses exceptional permeability, allowing the sterilizing agent to navigate intricate channels and complex geometries effortlessly.

 

  • Ideal for Premium & Fragile Instruments: Safely treats costly and sensitive medical assets, including cardiac catheters, vascular stents, intraocular lenses (IOLs), diagnostic endoscopes, fluid conduits, and precision cutting blades.

 

  • Extended Durability: Gentle action protects the integrity of specific medical accessories and single-use items, enabling safe, repeated utility.

 

Leading Indian Manufacturer & Control Options

As a premier producer of industrial ethylene oxide sterilizers in India, we engineer our systems across two distinct operational models:

 

  • Semi-Automatic Control Systems: Managed via conventional, hard-wired analog push buttons integrated directly onto the machine’s control interface for direct manual command.

 

  • Fully Automatic PLC-HMI Systems: Driven by an advanced programmable logic controller equipped with an intuitive touchscreen human-machine interface (HMI) mounted on the control panel for seamless, automated cycle execution.

Technical Specification of Industrial EO Gas Sterilizer

Model

AETOS – 2.6

AETOS – 4.5

AETOS – 8

Working Capacity in Cu. Ft.

2.6

4.5

8

Working Volume

70 Liters

125 Liters

200 Liters

Chamber Size

12” (W) x 12” (H) x 32”

 

12” (W) x 12” (H) x 54” (D) OR

15” (W) x 15” (H) x 36” (D)

20” (W) x 18” (H) x 38” (D) OR

16” (W) x 16” (H) x 54” (D)

Sterilant Gas

40 grams cartridge

100 grams cartridge

170 grams cartridge

Sterilization Cycle

Warm & Cold Cycles are possible.

Warm & Cold Cycles are possible.

Warm & Cold Cycles are possible.

Aeration

In-built aeration facility provided.

In-built aeration facility provided.

In-built aeration facility provided.

Utility

Compressed Air (100 psig)

Compressed Air (100 psig)

Compressed Air (100 psig)

Power Supply

1 K.W.

2 K.W.

2.5 K.W.

Power Voltage

220 volts, Single Phase, 50 Hertz

220 volts, Single Phase, 50 Hertz

220 volts, Single Phase, 50 Hertz

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Sterilization Equipment

Applications of Sterilization Equipment

Benefits of Industrial EO Gas Sterilizer

Versatile: Sterilizes items incompatible with steam, dry heat, or radiation.

Penetrating: Effective through multi-layer packaging.

Scalable: Handles bulk loads for manufacturing.

Work of Industrial EO Gas Sterilizer

The process occurs in a sealed chamber and involves four main phases, lasting 3–12 hours per cycle depending on load size and material:

 

  • Preconditioning/Humidification: Items are preconditioned (heated/humidified) to optimize EO penetration. Air is removed via vacuum.

 

  • Gas Exposure/Sterilization: EO gas is injected at low temperatures (25–55°C) and low pressure. Exposure time: 1–6 hours.

 

  • Evacuation: Vacuum and inert gas flushes remove EO.

 

  • Aeration/De-gassing: Heated air circulates to break down and vent residual EO, often in a separate chamber, until levels drop below 1 ppm for safety.

 

Advanced systems use microdoses and recirculation for efficiency, reducing gas use by up to 90% compared to older methods.

FAQ for Industrial EO Gas Sterilizer

The process delivers a Sterility Assurance Level (SAL) of 10⁻⁶, meaning the probability of a single viable microorganism surviving is one in a million. This high efficacy is achieved through EO gas’s ability to alkylate and disrupt the DNA and proteins of bacteria, viruses, fungi, and spores.

Yes. In addition to medical devices, it is suitable for preventing microbial growth and spoilage in seasonings, dried fruit kernels, packaged cereal grains, and similar products, making it useful beyond healthcare and pharmaceutical applications.

All areas that contact the product load are built from premium stainless steel—typically SS 304 or SS 316 grades—to ensure durability, corrosion resistance, and compliance with hygienic standards.

A full run averages roughly 8 hours. This includes preconditioning/humidification, EO gas exposure, and the subsequent aeration/evacuation phases needed to remove residual gas.

Two main options are available:

  • Semi-automatic systems controlled by conventional hard-wired analog push buttons.
  • Fully automatic PLC-HMI systems featuring a programmable logic controller and an intuitive touchscreen human-machine interface for automated cycle execution and monitoring.

Yes. Comprehensive qualification documentation packages covering Installation Qualification (IQ), Operational Qualification (OQ), and Design Qualification (DQ) can be supplied upon request to support regulatory compliance.

The units require compressed air at 100 psig. Power supply ranges from 1 kW to 2.5 kW depending on the model, typically at 220 V single-phase 50 Hz (adjustable to customer’s local voltage).

EO gas has exceptional permeability and diffusion properties. Combined with vacuum cycles, controlled humidity (typically 40–80 % RH), and recirculation, it reaches deep into multi-layer packaging, device channels, porous surfaces, and intricate geometries that steam or radiation cannot easily access.

Systems are offered in modular designs ranging from compact 0.5-cubic-meter models up to large 40-cubic-meter industrial units. Standard smaller models include AETOS-2.6 (≈70 L), AETOS-4.5 (≈125 L), and AETOS-8 (≈200 L), with corresponding EO cartridge sizes.

Countries We Export to

United States | Canada | Mexico | Brazil | Argentina | Chile | Colombia | Peru | Germany | United Kingdom | France | Italy | Spain | Netherlands | Belgium | Switzerland | Sweden | Austria | Denmark | Norway | Poland | Finland | Czech Republic | Hungary | Portugal | Ireland | Greece | Slovakia | Romania | Bulgaria | China | Japan | India | South Korea | Indonesia | Vietnam | Thailand | Malaysia | Philippines | Singapore | Bangladesh | Pakistan | Saudi Arabia | United Arab Emirates | Israel | Turkey | Iran | Qatar | Kuwait | South Africa | Nigeria | Egypt | Algeria | Morocco | Kenya | Ghana | Tunisia | Australia | New Zealand | Russia | Ukraine | Belarus | Kazakhstan | Taiwan | Hong Kong | South Sudan | Uzbekistan | Oman | Jordan | Bahrain | Sri Lanka | Myanmar | Lebanon | Mongolia | Ethiopia | Libya | Angola | Zambia | Zimbabwe | Mozambique | Ivory Coast | Senegal | Uganda | Tanzania | Botswana | Ecuador | Venezuela | Bolivia | Paraguay | Uruguay | Trinidad and Tobago | Panama | Guatemala | Costa Rica | Honduras | El Salvador | Nicaragua | Dominican Republic | Haiti | Cuba

Partner with Industry Experts

Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Countries We Export to

Algeria | Angola | Argentina | Australia | Austria | Bahrain | Bangladesh | Belarus | Belgium | Bolivia | Botswana | Brazil | Bulgaria | Canada | Chile | China | Colombia | Costa Rica | Cuba | Czech Republic | Denmark | Dominican Republic | Ecuador | Egypt | El Salvador | Ethiopia | Finland | France | Germany | Ghana | Greece | Guatemala | Haiti | Honduras | Hong Kong | Hungary | India | Indonesia | Iran | Ireland | Israel | Italy | Ivory Coast | Japan | Jordan | Kazakhstan | Kenya | Kuwait | Lebanon | Libya | Malaysia | Mexico | Mongolia | Morocco | Mozambique | Myanmar | Netherlands | New Zealand | Nicaragua | Nigeria | Norway | Oman | Pakistan | Panama | Paraguay | Peru | Philippines | Poland | Portugal | Qatar | Romania | Russia | Saudi Arabia | Senegal | Slovakia | Singapore | South Africa | South Korea | South Sudan | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Tanzania | Thailand | Trinidad and Tobago | Tunisia | Turkey | Uganda | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Uzbekistan | Venezuela | Vietnam | Zambia | Zimbabwe

Partner with Industry Experts

Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.

Contact Us

©Adinath International | Theme Developed By Pharma Machinery Manufacturer I Website updated on: 22 August 2026