R&D Ampoule Washing Machine

Description

The R&D Ampoule Washing Machine is a specialized piece of pharmaceutical equipment designed to efficiently and safely clean small glass ampoules, ranging in size from 1ml to 20ml, which are used in the production of injectable drugs. It is well-suited for use in research and development laboratories, pilot-scale production settings, and small to medium-sized pharmaceutical facilities. These machines are compact in design, offering excellent cleaning performance while maintaining full compliance with cGMP (Current Good Manufacturing Practices) standards.

 

Unlike high-speed rotary production models, R&D ampoule washers are semi-automatic, flexible, and space-efficient. They include separate washing circuits and filtered media to help prevent cross-contamination, making them ideal for handling small batch sizes and frequent product changes.

 

These washing machines ensure complete cleaning of both the inside and outside of ampoules using high-pressure jets of purified water, water for injection (WFI), and compressed air. This advanced cleaning process effectively eliminates particulate matter, residue, and microbial contaminants, significantly lowering the risk of contamination prior to filling and sealing the ampoules.

Working Principle of R&D Ampoule Washing Machine

  • Loading: Ampoules are placed in trays or dumped from boxes into the machine’s loading area.

 

  • Washing Cycle: Trays lower onto centering pins; needles align with ampoule necks for jet washing (inside/outside) using filtered WFI/purified water and air.

 

  • Drying and Unloading: Air jets dry residues; cycle ends automatically. Trays are removed for inspection.

 

  • Maintenance: Simple disassembly for cleaning; filters replaceable.

Technical Specification of R&D Ampoule Washing Machine

Model

AAVW 340P

Loading & Unloading

Manually

Washing Process

Automatic through PLC

Input Specification

2ml to 100ml vials and 1ml to 20ml ampoules

Production Output

Up to 100 ampoules/vials per minute(depends upon needle plate and operator’s efficiency)

Power Supply:

0.25 H.P.

Electrical Characteristics:

220 Volts, Single Phase, 50 Hertz

Net Weight:

120 Kgs. Approx.

Gross Weight:

250 Kgs. Approx

Net Dimension:

1200 mm (L) X 1020 mm (W) X 1080 mm (H) approx.

Case Dimensions:

1350 mm (L) X 1200 mm (W) X 1280 mm (H) approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of R&D Lab Machine

Applications of R&D Lab Machine

Advantages of R&D Ampoule Washing Machine

Compact Size and Small Footprint

Flexibility for Different Ampoule Sizes and Batch Sizes

High Cleaning Efficiency and Sterility

Compliance with Regulatory Standards

Improved Safety and Reduced Contamination Risk

Key Features of R&D Ampoule Washing Machine

  • Compact and GMP-Compliant Design: Built with stainless steel 316 contact parts, polycarbonate or HDPE filters (5-10 micron), and acrylic covers for visibility and safety. Machines auto-stop if the cover is lifted and resume from the interruption point.

 

  • Washing Mechanism: Multi-jet systems with solenoid valves and timers for sequential cycles (e.g., pre-wash, main wash, rinse, and air dry). Needles ensure positive pressure cleaning with minimal media usage.

 

  • Capacity and Flexibility: Handles 1ml-20ml ampoules (some models up to 25ml); suitable for vials too. Batch loading via trays (e.g., 100-200 ampoules per cycle) with adjustable sequences.

 

  • Controls: PLC/HMI touch screens for easy operation by semi-skilled staff; optional 21 CFR Part 11 compliance for data logging.

 

  • Safety and Validation: Includes IQ/OQ/PQ documentation; low bottle breakage rate (<0.5%).

FAQ for R&D Ampoule Washing Machine

The machine supports 1ml to 20ml ampoules and 2ml to 100ml vials. It offers flexibility for different sizes with quick changeovers, making it suitable for R&D and frequent product switches.

The model (AAVW 340P) can achieve an output of up to 100 ampoules/vials per minute, depending on the needle plate configuration and operator efficiency. It is designed for small-batch processing rather than high-speed commercial lines.

Ampoules are manually loaded into trays. The trays lower onto centering pins, and washing needles deliver sequential high-pressure jets of filtered water (purified/WFI) and compressed air for internal and external cleaning. Air jets then dry the ampoules, after which trays are manually unloaded. The process is PLC-controlled with automatic cycle completion.

  • Compact GMP-compliant design with SS 316 contact parts.
  • PLC/HMI touch screen control with solenoid valves and timers.
  • Acrylic top cover for visibility and safety interlock (auto-stop on lift, resume on close).
  • 5 or 10 micron replaceable filters.
  • Positive pressurized jets for efficient cleaning with minimal media usage.
  • IQ/OQ documentation support.

Yes. It features separate washing circuits, filtered media, and high-efficiency cleaning to remove particulates, residues, and microbial contaminants. All contact parts use FDA-approved materials (SS 316, Polycarbonate, HDPE, PP), supporting sterile conditions before filling and sealing.

It is widely used in:

  • Pharmaceutical Industry
  • Biotech Industry
  • Nutraceutical Industry
  • Herbal/Ayurvedic Industry
  • Cosmetic Industry
  • Chemical Industry

for cleaning containers used in injectable and sterile liquid production.

  • Small footprint ideal for R&D labs.
  • High cleaning efficiency and reduced contamination risk.
  • Flexibility for small batches and size changes.
  • Easy operation (even by semi-skilled operators).
  • Low power consumption (0.25 H.P.) and compliance with regulatory standards.

It uses a PLC/HMI-based touch screen for automatic washing cycles. Maintenance is simple: filters are replaceable, the machine disassembles easily for cleaning, and the safety cover provides clear visibility during operation.

Yes. Options include voltage adjustments for local power requirements, different needle plates, additional 21 CFR Part 11 compliance features, and customized washing sequences. IQ/OQ documentation is available, and the manufacturer offers tailored solutions for specific needs.

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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.

Adinath International manufactures high-precision vial powder filling machines and complete packaging lines, providing reliable, hygienic, and efficient solutions for global pharmaceutical industries.

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