Multijet Ampoule Washer

Q: What sizes of ampoules can the Multijet Ampoule Washer handle?

The machine handles 1ml to 20ml glass ampoules (and 2ml to 100ml vials with interchangeable change parts). It supports quick changeover using different needle plates (such as 56, 99, 189, 240, or 340 holes) and combi trays, making it highly versatile for multi-product facilities and varying batch sizes.

Q: What utilities are required and is the Multijet Ampoule Washer cGMP compliant?

Utilities required: Power: 0.25 HP, 220 Volts, Single Phase, 50 Hz (customizable) DM Water, Water for Injection (WFI), and Compressed Air Yes, it is fully cGMP compliant . It features SS 316/316L contact parts (or FDA-approved materials), online 5/10 micron filtration, pressure tank design, acrylic top cover with safety interlock, and polished finishes. It supports IQ/OQ documentation and optional PLC + HMI with 21 CFR Part 11 compliance.

Description

A Multijet Ampoule Washer is a semi-automatic, compact, and versatile washing machine designed for cleaning ampoules and vials in pharmaceutical settings, adhering to current Good Manufacturing Practices (cGMP) standards. It is widely used in small to medium-scale injectable production for ensuring sterility and hygiene of glass containers before filling. With its timer-operated solenoid valve system, this lab-scale small ampoule washer may observe up to six washing cycles in a single cycle. In medium-sized and small-scale injectable enterprises, multijet ampoule and vial washing machines are commonly utilized. The number of holes in combi trays, which are composed of cast nylon, varies according to the ampoules’ diameter. Different sizes of ampoules can be performed using a combination of needle plates with 53, 100, 189, 240, and 340 holes. Additionally, we have a Multijet Vial Washing Machine that is only used to clean vials.

Ampoules or vials are loaded manually (or via dump loading) into a combi tray.

The tray is placed in the machine and the handlebar is lowered to automatically center the washing needles into the container necks.

The transparent acrylic top cover is closed and the cycle is started.

The machine performs 6 sequential washes (3 water + 3 air) using filtered, pressurized jets for simultaneous internal and external cleaning.

After completion, the machine stops automatically with a buzzer and indicator light.

The cleaned containers are unloaded manually and are ready for sterilization or further processing.

Salient Features of Multijet Ampoule Washer

Compact GMP model.
Solenoid valve system with timer operated mechanism controlled from HMI.
PLC HMI based touch screen control panel.
Suitable to wash 1ml to 20ml ampoules and 2ml to 100ml vials.
Positive & pressurized jets through washing needle for pressure cleaning at minimum usages for washing media. Sound design concept of pressure tank for reverse & continuous supply of wash medias.
Both internal & external washing ensuring absolutely & continuous ampoule after sequential washing.

Acrylic top cover provided for clear view of washing during running of the machine.
On-line poly carbonates housing with P.P. replaceable filter cartridge of 5 or 10 micron of water for best possible washing.
All contact parts of washing media & Compressed Air are made from Stainless Steel316 or Polycarbonate HDPE or P.P. or any other FDA approved material.
Machine automatically stop in case of acrylic top cover lifted during cycle operation and machine re-start from the point when cover is pushed down.
Easy to operate machine can be operated by even semi-skilled operator.
IQ/OQ documentation can be provided.

Working Principle of Multijet Ampoule Washer

Ampoules are loaded in bulk onto combi tray if received in ready to dump boxes, which will have exactly same number of Ampoules and the pitch, as loading tray. Alternatively, each Ampoule/Vial has to be arranged into the tray individually. The loading tray is placed directly into the machine & the handlebar is lowered for automatic centering of washing needles into the Ampoules neck. The top cover is lowered & switch is operated for automatic sequential washing. Washing is performed from inside and outside of each individual Ampoule. Machine automatically stops after one complete washing cycle with buzzer sound and red-light indication. For removal of tray, reverse procedure is to be observed. Depending on loading & operator’s efficiency one can achieve 30 loading trays in an hour.

Multijet Ampoule and Vial Washing Machine is valued for its robust design, ease of operation (even by semi-skilled operators), and ability to deliver sterile, contaminant-free ampoules and vials, critical for pharmaceutical filling processes.

Technical Specification of Multijet Ampoule Washer

Model	AAVW 340P
Loading & Unloading	Manually
Washing Process	Automatic through PLC
Input Specification	2ml to 100ml vials and 1ml to 20ml ampoules
Production Output	Up to 100 ampoules/vials per minute(depends upon needle plate and operator’s efficiency)
Power Supply:	0.25 H.P.
Electrical Characteristics:	220 Volts, Single Phase, 50 Hertz
Net Weight:	120 Kgs. Approx.
Gross Weight:	250 Kgs. Approx
Net Dimension:	1200 mm (L) X 1020 mm (W) X 1080 mm (H) approx.
Case Dimensions:	1350 mm (L) X 1200 mm (W) X 1280 mm (H) approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Types of Ampoule Washing Machine

Ampoule Vial Washing Machine

Automatic Ampoule Washer

Automatic Rotary Ampoule Washing Machine

Automatic External Ampoule Washing Machine

High speed Ampoule Washing Machine

Lab Scale Ampoule Washing Machine

Multijet Ampoule Washing Machine

Linear Ampoule Washing Machine

Applications of Ampoule Washing Machine

Advantages of Multijet Ampoule Washer

Thorough Internal & External Cleaning with Positive Pressurized Multi-Jet Technology

Excellent Versatility for Different Container Sizes

High Resource Efficiency and Low Operational Costs

User-Friendly Operation with Built-in Safety Features

Full cGMP Compliance and Easy Validation

Washing Cycle of Multijet Ampoule Washer

Internal/External Washing	Washing Media
1st Wash	De-Mineralized Water
2nd Wash	Purified Air
3rd Wash	De-Mineralized Water
4th Wash	Purified Air
5th Wash	Water for Injection
6th Wash	Purified Air

Key Features of Multijet Ampoule Washer

Construction: Built with stainless steel (typically 316L for contact parts) and FDA-approved materials like polycarbonate, HDPE, or PP, ensuring durability and compliance with pharmaceutical standards.

Capacity: Washes ampoules from 1ml to 20ml (some models up to 25ml) and glass vials from 2ml to 100ml, with interchangeable change parts for different sizes.

Washing Mechanism: Utilizes positive and pressurized jets through washing needles for both internal and external cleaning, minimizing washing media usage. Typically includes six washing cycles per batch, using media like DM water, distilled water, or compressed air.

Operation:
- Ampoules/vials are loaded onto combi trays either manually or from ready-to-dump boxes.
- Trays are placed in the machine, and a handlebar aligns washing needles with container necks for precise cleaning.
- Sequential washing is controlled by a motorized cam-operated valve system, with optional timer-operated solenoid valves or microprocessor-controlled sequences.
- An acrylic top cover allows visibility during operation, and the machine stops automatically after a cycle with a buzzer and red-light indication.

Control System: Features PLC-based HMI touch screen panels for user-friendly operation and customizable washing cycles.

Additional Features:
- Pressure tank design for continuous and reverse supply of washing media.
- Online polycarbonate housing with 5 or 10-micron PP filter cartridges for optimal water filtration.
- Capable of processing up to 30 trays per hour, depending on operator efficiency (approximately 3,000 to 12,000 ampoules/vials per hour).

Applications: Ideal for R&D, pilot-scale production, and medium to small-scale injectable manufacturing in pharmaceutical, veterinary, and biotech industries.

Production Performance of Multijet Ampoule Washer

Jet Needles	Production Output
56 Holes Plate	1680 per hour approx. (56 holes plate x 30 cycles)
99 Holes Plate	2970 per hour approx. (56 holes plate x 30 cycles)
189 Holes Plate	5670 per hour approx. (56 holes plate x 30 cycles)
240 Holes Plate	7200 per hour approx. (56 holes plate x 30 cycles)
340 Holes Plate	10200 per hour approx. (56 holes plate x 30 cycles)

FAQ for Multijet Ampoule Washer

What is a Multijet Ampoule Washer and what is it used for?

The Multijet Ampoule Washer is a compact, semi-automatic washing machine designed for thorough internal and external cleaning of glass ampoules (and vials). It uses positive pressurized multi-jet technology to remove dust, particles, fibers, and residues, making containers ready for sterile filling of injectables, vaccines, or other pharmaceutical products. It is ideal for small to medium-scale production in pharmaceutical, biotech, veterinary, R&D labs, and pilot plants.

What sizes of ampoules can the Multijet Ampoule Washer handle?

The machine handles 1ml to 20ml glass ampoules (and 2ml to 100ml vials with interchangeable change parts). It supports quick changeover using different needle plates (such as 56, 99, 189, 240, or 340 holes) and combi trays, making it highly versatile for multi-product facilities and varying batch sizes.

How does the washing process work in the Multijet Ampoule Washer?

Ampoules are manually loaded into a combi tray. The tray is placed in the machine, and the handlebar lowers to center the washing needles. After closing the acrylic top cover, the automatic cycle begins. It performs 6 sequential washes (3 water + 3 air) using pressurized jets:

1st: De-Mineralized Water
2nd: Purified Air
3rd: De-Mineralized Water
4th: Purified Air
5th: Water for Injection (WFI)
6th: Purified Air

Internal and external cleaning occur simultaneously. The machine stops automatically with a buzzer after the cycle.

What is the production capacity of the Multijet Ampoule Washer?

The Multijet Ampoule Washer (typically Model AAVW 340P) can achieve up to 10,200 containers per hour (approximately 100–170 ampoules per minute depending on the needle plate and operator efficiency). It processes around 30 trays per hour. Output varies based on the selected needle plate and loading speed.

What utilities are required and is the Multijet Ampoule Washer cGMP compliant?

Utilities required:

Power: 0.25 HP, 220 Volts, Single Phase, 50 Hz (customizable)
DM Water, Water for Injection (WFI), and Compressed Air

Yes, it is fully cGMP compliant. It features SS 316/316L contact parts (or FDA-approved materials), online 5/10 micron filtration, pressure tank design, acrylic top cover with safety interlock, and polished finishes. It supports IQ/OQ documentation and optional PLC + HMI with 21 CFR Part 11 compliance.

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