

Antibiotic Powder Filling Machine are specialized pharmaceutical equipment designed for the precise, sterile filling of powdered antibiotics into vials or bottles. These machines are essential in pharmaceutical manufacturing because many antibiotics are unstable in liquid form and must be produced as dry powders for reconstitution later. The process involves high-speed dosing, often using auger or vacuum-pressure systems, while maintaining aseptic conditions to prevent contamination. Challenges include managing fine dust from potent ingredients, ensuring operator safety, and minimizing product loss—especially for cost-sensitive drugs. These machines typically operate in cleanroom Class B environments, comply with GMP standards, and integrate features like 100% in-process control (IPC) for weighing and filling accuracy.
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Duly cleaned containers are placed to the filling machine platform. From there containers transport towards the filling station with the help of conveyor belt. As soon as the bottle is sensed by bottle sensor, magnetic clutch starts to rotate which is mounted on the auger shaft. It fills the desired volume of powder to the container through Auger. After completion of filling process bottle transfers on conveyor for next capping operations.
Models | AI-APF 1 | AI-APF 2 | AI-APF 3 |
Production Output | Up to 30 bottles/minute | Up to 60 bottles/minute | Up to 90 bottles/minute |
Fill Volume | 5gms. to 60gms. in Single Dose System | 5gms. to 60gms. in Single Dose System | 5gms. to 60gms. in Single Dose System |
Container Size | Custom made as per required container size | Custom made as per required container size | Custom made as per required container size |
Filling Accuracy | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Powder |
Power Load | 2 H. P. | 3 H. P. | 4.5 H. P. |
Overall Dimension | 1810 mm (L) x 905 mm (W) x 1900 mm approx. | 2300 mm (L) x 905 mm (W) x 1900 mm approx. | 3000 mm (L) x 905 mm (W) x 1900 mm approx. |
Conveyor Height | 850 – 950 mm adjustable | 850 – 950 mm adjustable | 850 – 950 mm adjustable |
Electrical | 415VAC 3Phase and 220 VAC Single Phase Power Supply (50 Hz) with A.C. Drive | 415VAC 3Phase and 220 VAC Single Phase Power Supply (50 Hz) with A.C. Drive | 415VAC 3Phase and 220 VAC Single Phase Power Supply (50 Hz) with A.C. Drive |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
An Antibiotic Powder Filling Machine is a specialized auger-type volumetric filler designed for precise and sterile filling of dry antibiotic powders into bottles or vials. Powder is loaded into a hopper with an agitator for uniform flow. As bottles move on the conveyor, a sensor detects them and activates the magnetic clutch-driven auger to dispense the exact volume through a funnel. The machine ensures dust-free operation and maintains aseptic conditions critical for potent antibiotics.
The machine is available in three models:
Fill volume ranges from 5gms to 60gms per dose. Filling accuracy is ±2% to ±3%, depending on powder characteristics, bulk density uniformity, and environmental conditions.
It is ideal for filling antibiotic powders and other dry powders used in pharmaceuticals. The machine effectively handles both free-flowing and non-free-flowing powders. Container sizes are custom-made according to customer requirements. All product contact parts are made of SS316 (with Nylon/HDPE options) for hygiene and easy cleaning.
These features ensure high precision, sterility, and efficiency.
Yes, the machine is cGMP-compliant with hygienic stainless steel construction, making it suitable for pharmaceutical antibiotic production. Maintenance is minimal due to easy-to-clean and removable contact parts. Regular procedures include cleaning the hopper, auger, and funnels, along with maintaining controlled humidity and temperature for optimal powder flow. Quick changeover design helps minimize production downtime.
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Connect with our engineering team to discuss your specific production requirements. We provide customized, cGMP-compliant machinery solutions designed to optimize your manufacturing facility and maximize output.
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